引用次数
引用: 2,773
H-指数: 17
I10-指数 : 18
出版物: 38
The nuclear localization of 3'-phosphoinositide-dependent kinase-1 is dependent on its association with the protein tyrosine phosphatase SHP-1.
C.F. Sephton , D. Zhang , T.M. Lehmann , P.R. Pennington
Cellular Signalling 21 ( 11) 1634 -1644
11
2009
TDP-43 Is Directed to Stress Granules by Sorbitol, a Novel Physiological Osmotic and Oxidative Stressor
C. M. Dewey , B. Cenik , C. F. Sephton , D. R. Dries
Molecular and Cellular Biology 31 ( 5) 1098 -1108
356
2011
Activity-dependent FUS dysregulation disrupts synaptic homeostasis
C. F. Sephton , A. A. Tang , A. Kulkarni , J. West
Proceedings of the National Academy of Sciences of the United States of America 111 ( 44) 201406162
79
2014
Dephosphorylation of Akt in C6 cells grown in serum-free conditions corresponds with redistribution of p85/PI3K to the nucleus.
C. F. Sephton , D. D. Mousseau
Journal of Neuroscience Research 86 ( 3) 675 -682
7
2008
A postzygotic de novo NCDN mutation identified in a sporadic FTLD patient results in neurochondrin haploinsufficiency and altered FUS granule dynamics
Gaël Nicolas , Myriam Sévigny , François Lecoquierre , Florent Marguet
Acta neuropathologica communications 10 ( 1) 20
2
2022
NPRL2 inhibition of mTORC1 controls sodium channel expression and brain amino acid homeostasis
Jeremy B Hui , Jose Cesar Hernandez Silva , Mari Carmen Pelaez , Myriam Sévigny
Eneuro 9 ( 2)
2
2022
SAHA (VORINOSTAT) upregulates progranulin transcription: a rational therapeutic approach to frontotemporal dementia
Basar Cenik , Chantelle F Sephton , Colleen M Dewey , Xunde Xian
J Biol Chem 286 ( 18) 16101 -16108
5
2011
PROTEOLYSIS IN DIVERSE BIOLOGICAL SYSTEMS.
Steve A Maxwell , Zenggang Li , David Jaye , Scott Ballard
The Journal of Biological Chemistry 285 ( 49) 38740 -38740
2010
hnRNP A1B, a splice variant of HNRNPA1, is spatially and temporally regulated
Myriam Gagné , Jade-Emmanuelle Deshaies , Hadjara Sidibé , Yousri Benchaar
Frontiers in neuroscience 15 724307 -724307
7
2021
Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS
Mario Fernández Comaduran , Sandra Minotti , Suleima Jacob-Tomas , Javeria Rizwan
Cell Stress and Chaperones 29 ( 3) 359 -380
2024
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation
Geetika Aggarwal , Subhashis Banerjee , Spencer A Jones , Yousri Benchaar
Journal of Biological Chemistry 299 ( 12)
4
2023
Antisense oligonucleotides targeting miR‐29b binding site increase translation of progranulin protein: potential therapeutic strategy for progranulin‐deficient frontotemporal dementia
Geetika Aggarwal , Subhashis Banerjee , Spencer A Jones , Monica Pavlack
Alzheimer's & Dementia 18 e067828 -e067828
2022
Synaptic dysfunction in ALS and FTD: Anatomical and molecular changes provide insights into mechanisms of disease
Pauline A Gelon , Paul A Dutchak , Chantelle F Sephton
Frontiers in Molecular Neuroscience 15 1000183 -1000183
27
2022
Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition
Mari Carmen Pelaez , Antoine Desmeules , Pauline A Gelon , Bastien Glasson
Acta Neuropathologica Communications 11 ( 1) 182 -182
1
2023
GATOR1 Mutations Impair PI3 Kinase-Dependent Growth Factor Signaling Regulation of mTORC1
Maéline Muller , Jasmine Bélanger , Imane Hadj-Aissa , Conghao Zhang
International Journal of Molecular Sciences 25 ( 4) 2068 -2068
2024
https://www. jbc. org/cgi/doi/10.1074/jbc. RA120. 013801 The latest version is at
Myriam Sévigny , Isabelle Bourdeau Julien , Janani Priya Venkatasubramani , Jeremy B Hui
proteins 30 32 -32
Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation
Geetika Aggarwal , Subhashis Banerjee , Spencer A Jones , Yousri Benchaar
BioRxiv 2022.01. 12.476053 -2022.01. 12.476053
2022
Antisense oligonucleotide-based therapeutic strategy for progranulin-deficient frontotemporal dementia
Geetika Aggarwal , Subhashis Banerjee , Spencer A Jones , Monica Pavlack
Haloperidol induces the nuclear translocation of phosphatidylinositol 3'-kinase to disrupt Akt phosphorylation in PC12 cells.
Yunxiu Dai , Zelan Wei , Chantelle F Sephton , Di Zhang
Journal of Psychiatry & Neuroscience 32 ( 5) 323 -330
24
2007
Distinct Pools of β-Amyloid in Alzheimer Disease-Affected Brain: A Clinicopathologic Study. Commentary
Chantelle F SEPHTON , GANG YU , Yaakov STERN , Joshua R STEINERMAN
Archives of neurology (Chicago) 65 ( 7)
2008