Manu Sharma
机构: Assistant Professor of Neuroscience, Weill Cornell Medical College
每年引用次数
引用次数
引用: 7,896
H-指数: 27
I10-指数 : 30
出版物: 41
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
Jiajie Diao , Jacqueline Burré , Sandro Vivona , Daniel J Cipriano
eLife 2
334
2013
Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.
Nima N. Naseri , Burçe Ergel , Parinati Kharel , Yoonmi Na
Nature Structural & Molecular Biology 27 ( 2) 192 -201
2
2020
BETA- AND GAMMA-SYNUCLEINS MODULATE SYNAPTIC VESICLE-BINDING OF ALPHA-SYNUCLEIN
Kathryn E. Carnazza , Lauren Komer , André Pineda , Yoonmi Na
bioRxiv
2020
CASK Functions as a Mg2+-Independent Neurexin Kinase
Konark Mukherjee , Manu Sharma , Henning Urlaub , Gleb P. Bourenkov
Cell 133 ( 2) 328 -339
215
2008
Properties of native brain α-synuclein
Jacqueline Burré , Sandro Vivona , Jiajie Diao , Manu Sharma
Nature 498 ( 7453)
350
2013
Autosomal dominant neuronal ceroid lipofuscinosis - clinical features and molecular basis.
Nima Naseri , Manu Sharma , Milen Velinov
Clinical Genetics 99 ( 1) 111 -118
2021
The ΔF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR
Kai Du , Manu Sharma , Gergely L Lukacs
Nature Structural & Molecular Biology 12 ( 1) 17 -25
283
2005
Targeted stabilization of Munc18-1 function via pharmacological chaperones
Debra Abramov , Noah Guy Lewis Guiberson , Andrew Daab , Yoonmi Na
Embo Molecular Medicine 13 ( 1)
2021
CSPα knockout causes neurodegeneration by impairing SNAP‐25 function
Manu Sharma , Jacqueline Burré , Peter Bronk , Yingsha Zhang
The EMBO Journal 31 ( 4) 829 -841
108
2012
An autism‐associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor‐mediated synaptic transmission in hippocampus
Mark R Etherton , Katsuhiko Tabuchi , Manu Sharma , Jaewon Ko
The EMBO Journal 30 ( 14) 2908 -2919
105
2011
Microsecond Dissection of Neurotransmitter Release: SNARE-Complex Assembly Dictates Speed and Ca2+-Sensitivity
Claudio Acuna , Qingchen Guo , Jacqueline Burré , Manu Sharma
Neuron 82 ( 5) 1088 -1100
65
2014
Determinants of the nuclear localization of the heterodimeric DNA fragmentation factor (ICAD/CAD).
Delphine Lechardeur , Luke Drzymala , Manu Sharma , Danuta Zylka
Journal of Cell Biology 150 ( 2) 321 -334
77
2000
Cell Biology and Pathophysiology of α-Synuclein.
Jacqueline Burré , Manu Sharma , Thomas C. Südhof
Cold Spring Harbor Perspectives in Medicine 8 ( 3)
372
2018
Conformational and Temperature-sensitive Stability Defects of the ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator in Post-endoplasmic Reticulum Compartments
Manu Sharma , Mohamed Benharouga , Wei Hu , Gergely L. Lukacs
Journal of Biological Chemistry 276 ( 12) 8942 -8950
188
2001
The complexity of tau in Alzheimer's disease.
Nima N. Naseri , Hong Wang , Jennifer Guo , Manu Sharma
Neuroscience Letters 705 183 -194
34
2019
α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation
Jacqueline Burré , Manu Sharma , Thomas C. Südhof
Proceedings of the National Academy of Sciences of the United States of America 111 ( 40)
247
2014
CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity
Manu Sharma , Jacqueline Burré , Thomas C. Südhof
Nature Cell Biology 13 ( 1) 30 -39
176
2011
Misfolding diverts CFTR from recycling to degradation quality control at early endosomes
Manu Sharma , Francesca Pampinella , Csilla Nemes , Mohamed Benharouga
Journal of Cell Biology 164 ( 6) 923 -933
284
2004
The Role of the C Terminus and Na+/H+ Exchanger Regulatory Factor in the Functional Expression of Cystic Fibrosis Transmembrane Conductance Regulator in Nonpolarized Cells and Epithelia
Mohamed Benharouga , Manu Sharma , Jeffry So , Martin Haardt
Journal of Biological Chemistry 278 ( 24) 22079 -22089
72
2003
Cellular And Small Animal Models Of Neurodegenerative Diseases
Jacqueline Burré , Manu Sharma
JoVE (Journal of Visualized Experiments) ( 186) e64542
2022