The role of heparins and nano-heparins as therapeutic tool in breast cancer

Nikos A. Afratis , Konstantina Karamanou , Zoi Piperigkou , Demitrios H. Vynios
Glycoconjugate Journal 34 ( 3) 299 -307

15
2017
8.5 Pharmacological targeting of proteoglycans and metalloproteinases: an emerging aspect in cancer treatment

S Skandalis Spyros , C Gialeli , N Afratis , J Aletras Alexios
Extracellular Matrix: Pathobiology and Signaling. DE GRUYTER 785 -801

2
2012
Isolation, identification and biological action of hyaluronan oligomers

N Afratis , C Gialeli , A Giannis , N Karamanos
FEBS JOURNAL 279 250 -250

2012
22
2012
University of Galway Research Repository

Ignacio Sallent , Héctor Capella-Monsonís , Dimitrios I Zeugolis , I Sallent

2019
A guide to the composition and functions of the extracellular matrix.

Sylvie Ricard-Blum , Maurizio Onisto , Véronique Orian-Rousseau , Nikos K. Karamanos
FEBS Journal 15776

152
2021
The apparent competitive action of ECM proteases and cross-linking enzymes during fibrosis: Applications to drug discovery.

Nikolaos A. Afratis , Mordehay Klepfish , Nikos K. Karamanos , Irit Sagi
Advanced Drug Delivery Reviews 129 4 -15

21
2018
Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules

Zoi Piperigkou , Konstantina Karamanou , Nikolaos A Afratis , Panagiotis Bouris
Toxicology Letters 240 ( 1) 32 -42

15
2016
Novel Approaches for Extracellular Matrix Targeting in Disease Treatment

Nikolaos A. Afratis , Irit Sagi
The Extracellular Matrix 1952 261 -275

6
2019
Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma.

Ghazal Heidari-Hamedani , Romain R. Vivès , Amal Seffouh , Nikolaos A. Afratis
Cellular Signalling 27 ( 10) 2054 -2067

12
2015
Syndecans – key regulators of cell signaling and biological functions

Nikolaos A. Afratis , Dragana Nikitovic , Hinke A. B. Multhaupt , Achilleas D. Theocharis
FEBS Journal 284 ( 1) 27 -41

114
2017
Emerging insights into the role of matrix metalloproteases as therapeutic targets in fibrosis.

Nikolaos A. Afratis , Moises Selman , Annie Pardo , Irit Sagi
Matrix Biology 167 -179

34
2018
IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules

Nikolaos A. Afratis , Panagiotis Bouris , Spyros S. Skandalis , Hinke A. Multhaupt
Scientific Reports 7 ( 1) 40138

19
2017
LOXL2 Inhibition Paves the Way for Macrophage-Mediated Collagen Degradation in Liver Fibrosis.

Mordehay Klepfish , Tamar Gross , Milena Vugman , Nikolaos A. Afratis
Frontiers in Immunology 11 480

27
2020
A modified protocol for isolation and purity evaluation of a staphylococcal acidic polysaccharide by chromatography and capillary electrophoresis

Maria I. Krevvata , Nikos Afratis , Anastasia Spiliopoulou , Christina J. Malavaki
Biomedical Chromatography 25 ( 5) 531 -534

3
2011
Insights into the key roles of proteoglycans in breast cancer biology and translational medicine.

Achilleas D. Theocharis , Spyros S. Skandalis , Thomas Neill , Hinke A.B. Multhaupt
Biochimica et Biophysica Acta 1855 ( 2) 276 -300

99
2015
81
2015
Glycosaminoglycans: key players in cancer cell biology and treatment

Nikos Afratis , Chrisostomi Gialeli , Dragana Nikitovic , Theodore Tsegenidis
FEBS Journal 279 ( 7) 1177 -1197

316
2012
Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion.

Katerina Kouvidi , Aikaterini Berdiaki , Dragana Nikitovic , Pavlos Katonis
Journal of Biological Chemistry 286 ( 44) 38509 -38520

79
2011