Craig A. Townsend
机构: A. H. Corwin Professor of Chemistry, Johns Hopkins University
主页: jh.edu
每年引用次数
引用次数
引用: 18,117
H-指数: 70
I10-指数 : 237
出版物: 387
PD39 THE FATE OF N-ACETYLCYSTEAMINE THIOESTERS IN AROMATIC POLYKETIDE BIOSYNTHESIS
Susan W. Brobst , Craig A. Townsend
International Symposium on the Chemistry of Natural Products 1988 591
1988
Malonyl-Coenzyme-A Is a Potential Mediator of Cytotoxicity Induced by Fatty-Acid Synthase Inhibition in Human Breast Cancer Cells and Xenografts
Francis P. Kuhajda , Gojeb L. Frehywot , Michael L. Pinn , Ellen S. Pizer
Cancer Research 60 ( 2) 213 -218
482
2000
Fatty Acid Synthase Inhibition Triggers Apoptosis during S Phase in Human Cancer Cells
Francis P. Kuhajda , Susan M. Medghalchi , Michael L. Pinn , Gabriele V. Ronnett
Cancer Research 63 ( 21) 7330 -7337
293
2003
Ancient duplication and horizontal transfer of a toxin gene cluster reveals novel mechanisms in the cercosporin biosynthesis pathway
Melvin D. Bolton , Bart P.H.J Thomma , Yves Van de Peer , Yves Van de Peer
bioRxiv 100545
2
2017
Acyl Donor Stringency and Dehydroaminoacyl Intermediates in β-Lactam Formation by a Non-ribosomal Peptide Synthetase.
Craig A. Townsend , Darcie H. Long
ACS Chemical Biology 16 ( 5) 806 -812
3
2021
New insights into the formation of fungal aromatic polyketides
Jason M. Crawford , Craig A. Townsend
Nature Reviews Microbiology 8 ( 12) 879 -889
211
2010
Development of a penem antibiotic against Mycobacteroides abscessus.
Hunter R. Batchelder , Elizabeth Story-Roller , Evan P. Lloyd , Amit Kaushik
Communications Biology 3 ( 1) 741
2020
Reaction Models of the Oxidative Rearrangement of Averufin to 1'- Hydroxyversicolorone: The First Step in Dihydrobisfuran Formation in Aflatoxin Biosynthesis
Craig A. Townsend , Yasuo Isomura , Steven G. Davis , Julia A. Hodge
Tetrahedron 45 ( 8) 2263 -2276
32
1989
Features of DNA recognition for oriented binding and cleavage by calicheamicin
Stanley C. Mah , Mary Ann Price , Craig A. Townsend , Thomas D. Tullius
Tetrahedron 50 ( 5) 1361 -1378
16
1994
Hydroxyversicolorone: synthesis and incorporation of a new intermediate in aflatoxin biosynthesis
Craig A. Townsend , Paul R. O. Whittamore , Susan W. Brobst
Journal of The Chemical Society, Chemical Communications ( 11) 726 -728
10
1988
The role of molecular oxygen in clavulanic acid biosynthesis: evidence for a bacterial oxidative deamination
Craig A. Townsend , Walter J. Krol
Journal of The Chemical Society, Chemical Communications ( 18) 1234 -1236
19
1988
Clavulanic acid biosynthesis: the stereochemical course of β-lactam formation from chiral glycerol
Craig A. Townsend , Shi-shan Mao
Journal of The Chemical Society, Chemical Communications ( 2) 86 -89
10
1987
Stereochemical fate of (2S,4R)- and (2S,4S)-[4-2H]methionine in nocardicin A biosynthesis
Craig A. Townsend , Anne McE. Reeve , Gino M. Salituro
Journal of The Chemical Society, Chemical Communications ( 24) 1579 -1581
8
1988
Heterologous Expression, Isolation, and Characterization of Versicolorin B Synthase from Aspergillus parasiticus A KEY ENZYME IN THE AFLATOXIN B1 BIOSYNTHETIC PATHWAY
Jeffrey C. Silva , Craig A. Townsend
Journal of Biological Chemistry 272 ( 2) 804 -813
20
1997
Exploring Fungal Polyketide C-Methylation through Combinatorial Domain Swaps.
Philip A. Storm , Paramita Pal , Callie R. Huitt-Roehl , Craig A. Townsend
ACS Chemical Biology 13 ( 11) 3043 -3048
3
2018
Rücktitelbild: Characterization of an Anthracene Intermediate in Dynemicin Biosynthesis (Angew. Chem. 20/2018)
Douglas R. Cohen , Craig A. Townsend
Angewandte Chemie 130 ( 20) 6062 -6062
2018
A Method for Prediction of the Locations of Linker Regions within Large Multifunctional Proteins, and Application to a Type I Polyketide Synthase
Daniel W. Udwary , Matthew Merski , Craig A. Townsend
Journal of Molecular Biology 323 ( 3) 585 -598
100
2002
Partitioning of tetrahydro- and dihydrobisfuran formation in aflatoxin biosynthesis defined by cell-free and direct incorporation experiments
Sean M. McGuire , Susan W. Brobst , Todd L. Graybill , Kollol Pal
Journal of the American Chemical Society 111 ( 21) 8308 -8309
19
1989
The timing of aromatic deoxygenation in aflatoxin biosynthesis
Todd L. Graybill , Kollol Pal , Sean M. McGuire , Susan W. Brobst
Journal of the American Chemical Society 111 ( 21) 8306 -8308
12
1989
Cell-Free Biosynthesis of Nocardicin A from Nocardicin E and S-Adenosylmethionine
Brenda A. Wilson , Shanta. Bantia , Gino M. Salituro , Anne M. Reeve
Journal of the American Chemical Society 110 ( 24) 8238 -8239
12
1988