Christopher Kontos
机构: Professor of Medicine, Duke University Medical Center
每年引用次数
引用次数
引用: 8,283
H-指数: 50
I10-指数 : 76
出版物: 164
Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis.
KG Peters , A Coogan , D Berry , J Marks
British Journal of Cancer 77 ( 1) 51 -56
156
1998
PI3K and TGF beta pathways interact functionally and therapeutically to regulate cellular motility and invasion in malignant glioma.
S Sathorn-sumetee , AB Hjelmeland , MD Hjelmeland , Q Shi
CLINICAL CANCER RESEARCH 11 ( 24) 9134S -9134S
2005
The endothelial receptor tyrosine kinase Tie2 activates phosphatidylinositol 3-kinase and Akt and mediates endothelial cell survival.
CD Kontos , S Sankar , TP Stauffer , JD York
Circulation 98 ( 17) 463 -463
1
1998
Requirement of ankyrin-B in the intracellular targeting of IP3 receptor calcium release channels in diverse tissues
AO Gramolini , PJ Mohler , ME Ali , LH Davis
MOLECULAR BIOLOGY OF THE CELL 12 303A -303A
2001
Tie2 signaling is required for exercise-induced skeletal muscle angiogenesis
RY Ro , R Waters , Z Yan , B Annex
Circulation 110 ( 17) 173 -173
1
2004
2.3. Systems biology modeling of junctional localization and downstream signaling of the Ang–Tie signaling pathway
Y Zhang , CD Kontos , BH Annex , AS Popel
SYSTEMS BIOLOGY MODELING OF COMPLEX CELLULAR SIGNALING NETWORKS IN HUMAN DISEASES 113 -113
2024
CALL FOR PAPERS-Computational Modeling of Physiological Genomics-Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: Effects of transendothelial and lymphatic macromolecular transport
FTH Wu , MO Stefanini , F Mac Gabhann , CD Kontos
Physiological Genomics 38 29 -29
2009
An Engineered VEGF-Activating Zinc Finger Transcription Factor Induces Angiogenesis and Bone Marrow Endothelial Progenitor Cell Production
GK Lam , RG Mitchell , BH Annex , CD Kontos
Journal of Endovascular Therapy 13 I16 -I16
2006
Therapeutic angiogenesis in pigs with chronic myocardial ischemia using Ad-VEGF165 gene injections does not require localization to the ischemic zone
T Ueno , CD Kontos , BH Annex , J Cui
CIRCULATION 104 ( 17) 69 -69
2001
Systemic administration of angiopoietin-2, but not angiopoietin-1, inhibits progression of arteriosclerosis in ApoE (-/-) mice
XL Niu , S Ahmed , JH Huang , M Cudmore
CIRCULATION 108 ( 17) 26 -26
2003
Negative regulation of Tie2 autophosphorylation and signal transduction by the protein tyrosine phosphatase Shp2
PB Liao , EH Cha , M Davis , KG Peters
CIRCULATION 102 ( 18) 298 -298
2000
Targeting PTEN alters angiogenesis and ventricular remodeling in a murine left ventricular cryoinjury model
JH Huang , W Tao , PJ Goldschmidt-Clermont , CD Kontos
CIRCULATION 108 ( 17) 73 -73
2003
Overexpression of PTEN inhibits beta3 integrin-mediated signal transduction in vascular smooth muscle cells
JH Huang , CD Kontos , A Pathak , GA Stouffer
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 25 ( 5) E46 -E46
2005
A Novel Inhibitor of Angiopoietin-1 Blocks Tie2 Signaling
RR White , CP Rusconi , CD Kontos , BA Sullenger
SURGICAL FORUM-CHICAGO- 218 -220
5
2001
The p85 subunit of phosphatidylinositol 3'-kinase associates with the endothelium-specific receptor tyrosine kinase Tek
CD Kontos , LW Huang , WP Yang , M Blanar
Circulation 94 ( 8) 2357 -2357
1
1996
Adenovirus-mediated intra-artertal delivery of PTEN inhibits neointimal hyperplasia
JH Huang , CD Kontos
CIRCULATION 106 ( 19) 274 -274
2002
Characterization of ASPR1, a novel Tie1-interacting protein
RY Ro , XL Niu , PB Liao , KG Peters
CIRCULATION 106 ( 19) 268 -268
2002
A novel inhibitor of Angiopoietin-1 disrupts Tie2-mediated endothelial cell survival
RR White , CP Rusconi , BA Sullenger , CD Kontos
CIRCULATION 104 ( 17) 315 -315
2001
The endothelial receptor tyrosine kinase Tie1 inhibits apoptosis through a phosphatidylinositol 3-kinase-dependent, AKT-independent mechanism
CD Kontos , EH Cha , KG Peters
CIRCULATION 102 ( 18) 297 -297
2000
The endothelial receptor tyrosine kinases Tie1 and Tie2 induce tyrosine phosphorylation of the inositol phosphatase SHIP2
CD Kontos , EH Cha , KG Peters
CIRCULATION 100 ( 18) 770 -771
1999