A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis.
Jana Korduláková , Stefan Chassaing , Stefan Chassaing , Maria Rosalia Pasca
ACS Infectious Diseases 7 ( 3) 552 -565
2021
Promiscuous Targets for Antitubercular Drug Discovery: The Paradigm of DprE1 and MmpL3
Giulia Degiacomi , Juan Manuel Belardinelli , Maria Rosalia Pasca , Edda De Rossi
Applied Sciences 10 ( 2) 623
12
2020
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression
Giulia Degiacomi , Andrej Benjak , Jan Madacki , Francesca Boldrin
Scientific Reports 7 ( 1) 43495 -43495
46
2017
RETRACTED ARTICLE: Antituberculars which target decaprenylphosphoryl-β-D-ribofuranose 2′-oxidase DprE1: state of art
Silvia Buroni , Maria Rosalia Pasca , Ana Luisa de Jesus Lopes Ribeiro , Giulia Degiacomi
Applied Microbiology and Biotechnology 94 ( 4) 907 -916
4
2012
In vitro Study of Bedaquiline Resistance in Mycobacterium tuberculosis Multi-Drug Resistant Clinical Isolates.
Giulia Degiacomi , José Camilla Sammartino , Virginia Sinigiani , Paola Marra
Frontiers in Microbiology 11 ( 559469) 559469 -559469
6
2020
GarA is an essential regulator of metabolism in Mycobacterium tuberculosis
Marcello Ventura , Barbara Rieck , Francesca Boldrin , Giulia Degiacomi
Molecular Microbiology 90 ( 2) 356 -366
62
2013
First triclosan-based macrocyclic inhibitors of InhA enzyme.
Frédéric Rodriguez , Nathalie Saffon , José Camilla Sammartino , Giulia Degiacomi
Bioorganic Chemistry 95 103498
4
2020
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.
Leonardo Astolfi Rosado , Khadija Wahni , Giulia Degiacomi , Brandan Pedre
Journal of Biological Chemistry 292 ( 32) 13097 -13110
9
2017
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals Are Uniformly Susceptible to Benzothiazinones
Maria Rosalia Pasca , Giulia Degiacomi , Ana Luisa de Jesus Lopes Ribeiro , Francesca Zara
Antimicrobial Agents and Chemotherapy 54 ( 4) 1616 -1618
63
2010
Nitric oxide-releasing compounds for the treatment of lung infections
Laurent R. Chiarelli , Giulia Degiacomi , Anna Egorova , Vadim Makarov
Drug Discovery Today 26 ( 2) 542 -550
5
2021
Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy.
Haoting Hsu , Sarah Boudova , Godfrey Mvula , Titus H Divala
Cellular Immunology 359 104244 -104244
2021
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis.
Ana Luisa de Jesus Lopes Ribeiro , Giulia Degiacomi , Fanny Ewann , Silvia Buroni
PLOS ONE 6 ( 11)
35
2011
A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors
Marta Esposito , Sára Szadocka , Giulia Degiacomi , Beatrice S. Orena
ACS Infectious Diseases 3 ( 6) 428 -437
19
2017
Promoter mutagenesis for fine-tuning expression of essential genes in Mycobacterium tuberculosis
Francesca Boldrin , Giulia Degiacomi , Agnese Serafini , Gaëlle S. Kolly
Microbial Biotechnology 11 ( 1) 238 -247
7
2018
Whole cell screen based identification of spiropiperidines with potent antitubercular properties
Subramanyam J. Tantry , Giulia Degiacomi , Sreevalli Sharma , Lalit kumar Jena
Bioorganic & Medicinal Chemistry Letters 25 ( 16) 3234 -3245
23
2015
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug.
Giorgia Mori , Beatrice Silvia Orena , Laurent R. Chiarelli , Giulia Degiacomi
Frontiers in Microbiology 11 292
2020
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK.
Laurent R. Chiarelli , Giorgia Mori , Beatrice Silvia Orena , Marta Esposito
Scientific Reports 8 ( 1) 3187
13
2018
Micrococcin P1 – A bactericidal thiopeptide active against Mycobacterium tuberculosis
Giulia Degiacomi , Yoann Personne , Guillaume Mondésert , Xueliang Ge
Tuberculosis 100 95 -101
10
2016
Biological and Structural Characterization of the Mycobacterium Smegmatis Nitroreductase Nfnb, and its Role in Benzothiazinone Resistance
Giulia Manina , Marco Bellinzoni , Maria Rosalia Pasca , João Neres
Molecular Microbiology 77 ( 5) 1172 -1185
53
2010
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
Giorgia Mori , Laurent R Chiarelli , Marta Esposito , Vadim Makarov
Chemistry & Biology 22 ( 7) 917 -927
35
2015