The factor V Leiden mutation results in the in vivo loss of a critical FV anticoagulant function

R. J. Westrick , S. L. Manning , D. T. Eitzman , D. Ginsburg
Wiley Periodicals, Inc.

2
2003
Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele.

R. J. Westrick , K. L. Mohlke , L. M. Korepta , A. Y. Yang
Proceedings of the National Academy of Sciences of the United States of America 107 ( 39) 16904 -16909

17
2010
A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11

K. L. Mohlke , W. C. Nichols , R. J. Westrick , E. K. Novak
Proceedings of the National Academy of Sciences of the United States of America 93 ( 26) 15352 -15357

56
1996
Thrombus stability explains the factor V Leiden paradox: a mouse model

S. A. Shaya , R. J. Westrick , P. L. Gross
Blood Advances 3 ( 21) 3375 -3378

2
2019
The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival

K. M. Dougherty , J. M. Pearson , A. Y. Yang , R. J. Westrick
Proceedings of the National Academy of Sciences of the United States of America 96 ( 2) 686 -691

100
1999
Backseat drivers: passenger mutations take control of experimental phenotypes

B. J. M. van Vlijmen , R. J. Westrick
Journal of Thrombosis and Haemostasis 14 ( 8) 1615 -1617

2016
Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice

Y. Zhang , S. N. Zolov , C. Y. Chow , S. G. Slutsky
Proceedings of the National Academy of Sciences of the United States of America 104 ( 44) 17518 -17523

176
2007
Modifier genes for disorders of thrombosis and hemostasis

R. J. WESTRICK , D. GINSBURG
Journal of Thrombosis and Haemostasis 7 132 -135

18
2009
Early death of factor v leiden hemizygous mice : a fatal absence of wild type FV anticoagulant function

R.J. Westrick , D. Ginsburg , A.C.A. Cleuren , P.H. Reitsma
9 57 -57

2011
AN ENU MUTAGENESIS SCREEN FOR DOMINANT GENETIC MODIFIERS OF THROMBOSIS IN THE FACTOR 5 LEIDEN MOUSE

R.J. Westrick , S.L. Manning , M.E. Winn , G.M. Stotz
Journal of Thrombosis and Haemostasis 5 P -W

2007
Identification of a strain specific modifier gene for thrombosis in factor V Leiden mice.

DT Eitzman , RJ Westrick , J Cui , A Yang
Blood 94 ( 10) 373A -373A

1
1999
Plasminogen activator inhibitor type 2 (PAI-2) deficiency promotes tumor growth in murine models of malignancy.

L Payne , RJ Westrick , K Dougherty , D Ginsburg
Blood 92 ( 10) 474A -474A

1
1998
A novel genetic mechanism for reduced plasma von Willebrand factor level in the RIIIS/J mouse.

KL Mohlke , AA Purkayasatha , RJ Westrick , PL Smith
Blood 90 ( 10) 1774 -1774

1
1997
Identification of ENU-induced and strain modifier genes for factor V Leiden dependent thrombosis in the mouse

RJ Westrick , G Zhu , SL Manning , AY Yang
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 9 57 -57

2011
A sensitized ENU mouse mutagenesis screen to identify genetic modifiers of thrombosis in Factor V Leiden.

RJ Westrick , SL Manning , A Aiyagari , DR Siemieniak
BLOOD 102 ( 11) 540A -540A

2003
A sensitized ENU mutagenesis screen for dominant genetic modifiers of thrombosis in the factor V Leiden mouse

RJ Westrick , SL Manning , DR Siemieniak , A Aiyagari
Wiley Periodicals, Inc.

2003
Expression of an N-acetylgalactosamine transferase is a major modifier of murine plasma von Willebrand factor levels

KL Mohlke , AA Purkayastha , RJ Westrick , PL Smith
GLYCOBIOLOGY 8 ( 11) 1115 -1116

1998