Dos Sarbassov
机构: Professor of Biology, Nazarbayev University
每年引用次数
引用次数
引用: 25,382
H-指数: 29
I10-指数 : 37
出版物: 64
Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton
Dos D. Sarbassov , Siraj M Ali , Do-Hyung Kim , David A Guertin
Current Biology 14 ( 14) 1296 -1302
3,192
2004
Integrity of mTORC2 is dependent on the rictor Gly-934 site.
R Aimbetov , C-H Chen , O Bulgakova , D Abetov
Oncogene 31 ( 16) 2115 -2120
18
2012
Rictor regulates cell migration by suppressing RhoGDI2
N K Agarwal , C-H Chen , H Cho , D R Boulbès
Oncogene 32 ( 20) 2521 -2526
49
2013
Учредители: Национальный центр биотехнологии
FG FAZYL , DA BEGIMBETOVA , KU BATYRBEKOV , Z SPATAEV
EURASIAN JOURNAL OF APPLIED BIOTECHNOLOGY ( 3) 75 -81
ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies
Jo Ishizawa , Kensuke Kojima , Dhruv Chachad , Peter Ruvolo
Science Signaling 9 ( 415)
139
2016
Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML
Zhihong Zeng , Dos D. Sarbassov , Ismael J. Samudio , Karen W. L. Yee
Blood 109 ( 8) 3509 -3512
309
2007
Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex.
Dos D. Sarbassov , David M. Sabatini
Journal of Biological Chemistry 280 ( 47) 39505 -39509
198
2005
High-throughput profiling of signaling networks identifies mechanism-based combination therapy to eliminate microenvironmental resistance in acute myeloid leukemia.
Zhihong Zeng , Wenbin Liu , Twee Tsao , YiHua Qiu
Haematologica 102 ( 9) 1537 -1548
9
2017
Formation of mammalian preribosomes proceeds from intermediate to composed state during ribosome maturation.
Danysh A. Abetov , Vladimir S. Kiyan , Assylbek A. Zhylkibayev , Dilara A. Sarbassova
Journal of Biological Chemistry 294 ( 28) 10746 -10757
2
2019
mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
Do-Hyung Kim , Dos D. Sarbassov , Siraj M. Ali , Jessie E. King
Cell 110 ( 2) 163 -175
3,454
2002
Endoplasmic reticulum is a main localization site of mTORC2.
Delphine R. Boulbés , Tattym Shaiken , Dos D. Sarbassov
Biochemical and Biophysical Research Communications 413 ( 1) 46 -52
57
2011
Isolation of the mTOR Complexes by Affinity Purification
Dos D. Sarbassov , Olga Bulgakova , Rakhmet I. Bersimbaev , Tattym Shaiken
Methods in Molecular Biology 821 59 -74
7
2012
Rictor encounters RhoGDI2: the second pilot is taking a lead.
Nitin K. Agarwal , Dubek Kazyken , Dos D. Sarbassov
Small GTPases 4 ( 2) 102 -105
3
2013
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Meghan Morrison Joly , Michelle M. Williams , Donna J. Hicks , Bayley Jones
Breast Cancer Research 19 ( 1) 74 -74
32
2017
Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts.
Dos D. Sarbassov , Linda G. Jones , Charlotte A. Peterson
Molecular Endocrinology 11 ( 13) 2038 -2047
78
1997
Insulin receptor substrate-1 and phosphatidylinositol 3-kinase regulate extracellular signal-regulated kinase-dependent and -independent signaling pathways during myogenic differentiation.
Dos D. Sarbassov , Charlotte A. Peterson
Molecular Endocrinology 12 ( 12) 1870 -1878
57
1998
Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers
Meghan Morrison Joly , Donna J. Hicks , Bayley Jones , Violeta Sanchez
Cancer Research 76 ( 16) 4752 -4764
39
2016
The mTOR (Mammalian Target of Rapamycin) Kinase Maintains Integrity of mTOR Complex 2
Chien-Hung Chen , Dos D. Sarbassov
Journal of Biological Chemistry 286 ( 46) 40386 -40394
41
2011
Rictor Phosphorylation on the THR-1135 Site Does Not Require Mammalian Target of Rapamycin Complex 2
Delphine Boulbes , Chien-Hung Chen , Tattym Shaikenov , Nitin K. Agarwal
Molecular Cancer Research 8 ( 6) 896 -906
55
2010
FoxO Transcription Factors Promote AKT Ser473 Phosphorylation and Renal Tumor Growth in Response to Pharmacologic Inhibition of the PI3K–AKT Pathway
Aifu Lin , Hai-long Piao , Li Zhuang , Dos D. Sarbassov
Cancer Research 74 ( 6) 1682 -1693
80
2014