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Nature 603 ( 7901) 439 -444
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2022
Application of Machine Learning and Reaction Optimization for the Iterative Improvement of Enantioselectivity of Cinchona-Derived Phase Transfer Catalysts
Katrina W Lexa , Kevin M Belyk , Jeremy Henle , Bangping Xiang
Organic Process Research \& Development 26 ( 3) 670 -682
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2021
Manufacturing Process Development for Uprifosbuvir (MK-3682): A Green and Sustainable Process for Preparing Penultimate 2′-Deoxy-α-2′-Chloro-β-2′-Methyluridine
Peter E Maligres , Feng Peng , Ralph Calabria , Louis-Charles Campeau
Organic Process Research & Development 26 ( 9) 2728 -2738
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The Catalysis Laboratory at Merck: 20 Years of Catalyzing Innovation
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ACS Catalysis 13 ( 1) 475 -503
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Harnessing the Power of Catalysis for the Synthesis of CRTH2 Antagonist MK-1029
Rebecca T Ruck , Jun Pan , Rishi G Vaswani , Birgit Kosjek
Organic Process Research & Development 26 ( 3) 648 -656
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Feng Xu , Richard Desmond , Guy R Humphrey , Hongming Li
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Empowering Women in Organic Chemistry (EWOC) at Five Years: Giving Back and Getting Back
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Biochemistry 62 ( 20) 2895 -2901
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Correction to “Application of Machine Learning and Reaction Optimization for the Iterative Improvement of Enantioselectivity of Cinchona-Derived Phase Transfer Catalysts”
Katrina W Lexa , Kevin M Belyk , Jeremy Henle , Bangping Xiang
Organic Process Research & Development 28 ( 1) 326 -326
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A modular synthesis of 2-alkyl-and 2-arylchromans via a three-step sequence
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Introduction to Industrial Applications of Asymmetric Synthesis
Rebecca T Ruck , Louis-Charles Campeau
Elsevier
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Timothy A Blizzard , Helen Chen , Candido Gude , Jeffrey D Hermes
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Composto, composição farmacêutica, método para tratar uma infecção bacteriana, uso do composto, e, processo para preparar um composto
Timothy A Blizzard , Helen Chen , Candido Gude , Jeffrey D Hermes
2021
Discovery of Ruzasvir (MK-8408): A Potent, Pan-Genotype HCV NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Polymorphisms.
Ling Tong , Wensheng Yu , Lei Chen , Oleg Selyutin
Journal of Medicinal Chemistry 60 ( 1) 290 -306
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Structure–activity relationships of proline modifications around the tetracyclic-indole class of NS5A inhibitors
Ling Tong , Wensheng Yu , Craig A Coburn , Lei Chen
Bioorganic & Medicinal Chemistry Letters 26 ( 21) 5354 -5360
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Discovery of MK-6169, a Potent Pan-Genotype Hepatitis C Virus NS5A Inhibitor with Optimized Activity against Common Resistance-Associated Substitutions
Wensheng Yu , Ling Tong , Oleg Selyutin , Lei Chen
Journal of Medicinal Chemistry 61 ( 9) 3984 -4003
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Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids
Ian Mangion , Mark A Huffman , Rebecca T Ruck , Joseph Lynch
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Ian Mangion , Nelo Rivera , Rebecca T Ruck , Michael Shelvin
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