MEKK1 plays a critical role in activating the transcription factor C/EBP-β-dependent gene expression in response to IFN-γ
S. K. Roy , J. Hu , Q. Meng , Y. Xia
Proceedings of the National Academy of Sciences of the United States of America 99 ( 12) 7945 -7950
122
2002
Oxygen-induced changes in protein synthesis and cell proliferation in cultured lung slices.
P. S. Shapiro , F. E. Casty , W. S. Stirewalt , K. O. Leslie
American Journal of Physiology-lung Cellular and Molecular Physiology 267 ( 6)
7
1994
Phosphorylation regulates nucleophosmin targeting to the centrosome during mitosis as detected by cross-reactive phosphorylation-specific MKK1/MKK2 antibodies.
Hyukjin CHA , Chad HANCOCK , Surabhi DANGI , Dony MAIGUEL
Biochemical Journal 378 ( 3) 857 -865
49
2004
MAP kinase signaling pathways and regulation of cell cycle progression in mammalian cells
Paul S SHAPIRO
Recent research developments in molecular & cellular biology 207 -222
2001
The separation of mixed MnO₂-SiO₂ dispersions by selective polymer flocculation.
Paul Sauveur Shapiro
1965
The Separation of Mixed MnO2-SiO2 Dispersions by Selective Polymer Flocculation
Paul Sauveur Shapiro
1965
Induction of apoptosis by novel substrate selective extracellular signal-regulated kinase (ERK) inhibitors
Paul Shapiro , Sarice R Smith
The FASEB Journal 22
2008
The role of the MAP kinase transduction pathway in regulating S100B in melanoma
Michele I Vitolo , Kira Gianni , Paul Shapiro , David J Weber
The FASEB Journal 23
2009
Novel extracellular-signal regulated kinase (ERK) substrate inhibitors mediate apoptotic signaling
Paul Shapiro , Sarice R Boston , Alexander D MacKerell
The FASEB Journal 24
2010
Abstract B132: Functionalization of the primary amino group of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione enhances selectivity and specificity of the inhibition of ERK substrate docking domains.
Steven Fletcher , Kerrick Nevels , Kwan-Young Jeong , Ramin Samadani
Molecular Cancer Therapeutics 10
2011
Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)
Ursula A. Germann , Brinley F. Furey , William Markland , Russell R. Hoover
Molecular Cancer Therapeutics 16 ( 11) 2351 -2363
170
2017
Identification of ERK2-Substrate Protein Inhibitors via Virtual Screening, Biological Assays and X-Ray Crystallography
Taiji Oashi , Jun Zhang , Kimberly Burkhard , U. Deva Priyakumar
Biophysical Journal 100 ( 3) 2 -4
2011
A temperature-dependent conformational shift in p38α MAPK substrate–binding region associated with changes in substrate phosphorylation profile
Daniel Deredge , Patrick L. Wintrode , Mohan E. Tulapurkar , Ashish Nagarsekar
Journal of Biological Chemistry 294 ( 34) 12624 -12637
4
2019
P3-421: Identification of structural determinants on PS-1 and PS-2 that affect inhibitor potency
Guriqbal Basi , Mei Yu , Marty Neitzel , Jennifer Marugg
Alzheimers & Dementia 2 ( 3)
2006
P4-049: The luminal juxtamembrane domain of beta-amyloid precursor protein regulates gamma-secretase-dependent cleavage
Zhao Ren , Dale Schenk , Sukanto Sinha , Guriq Basi
Alzheimers & Dementia 2 ( 3)
2006
Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation.
Meng Qiao , Paul Shapiro , Matthew Fosbrink , Horea Rus
Journal of Biological Chemistry 281 ( 11) 7118 -7128
90
2006
Mu opioid receptor mutant, T394A, abolishes opioid-mediated adenylyl cyclase superactivation
Hongyan Wang , Wei Guang , Elisabeth Barbier , Paul Shapiro
NeuroReport 18 ( 18) 1969 -1973
11
2007
A promiscuous kinase inhibitor reveals secrets to cancer cell survival
Paul Shapiro
Journal of Biological Chemistry 294 ( 21) 8674 -8675
2019
Inhibition of mixed-lineage kinase (MLK) activity during G2-phase disrupts microtubule formation and mitotic progression in HeLa cells
Hyukjin Cha , Surabhi Dangi , Carolyn E. Machamer , Paul Shapiro
Cellular Signalling 18 ( 1) 93 -104
27
2006
Discovering New MAP Kinase Inhibitors
Paul Shapiro
Chemistry & Biology 13 ( 8) 807 -809
3
2006