SC-31RATIONAL DESIGN OF A PI3-KINASE/mTOR INHIBITOR CYTOTOXIC TO BRAIN CANCER STEM CELLS UNDER HYPOXIA

N. Vad , S. Jagannathan , K. Sumita , M. Abdel-Malek
Neuro-oncology 16

1
2014
Efficacy of acetaminophen in skin B16-F0 melanoma tumor-bearing C57BL/6 mice

Nikhil M Vad , Shashi K Kudugunti , Daniel Graber , Nathan Bailey
International journal of oncology 35 ( 1) 193 -204

16
2009
ER stress, unfolded protein response, and autophagy are pro-survival responses to fenretinide+ safingol treatment in GBM cells

Nikhil M Vad , Dong Wang , Barry J Maurer
Cancer Research 76 ( 14_Supplement) 4656 -4656

2016
Structure-toxicity relationship of phenolic analogs as anti-melanoma agents: An enzyme directed prodrug approach

Nikhil M Vad , Prabodh K Kandala , Sanjay K Srivastava , Majid Y Moridani
Chemico-Biological Interactions 183 ( 3) 462 -471

9
2010
PHARMACOKINETICS, PHARMACODYNAMICS AND DRUG METABOLISM: Metabolic Bioactivation and Toxicity of Ethyl 4-Hydroxybenzoate in Human SK-MEL-28 Melanoma Cells

Nikhil M VAD , Imam H SHAIK , Reza MEHVAR , Majid Y MORIDANI
Journal of pharmaceutical sciences 97 ( 5) 1934 -1945

2008
Curcumin induced toxicity towards human SK-MEL-28 melanoma cells

Nikhil Vad , Majid Moridani
Cancer Research 67 3966 -3966

2007
2008
2006
2015
Correlation of Non-Coding RNA Expression with Response to Proteasome Inhibitors in Multiple Myeloma

Ehsan Malek , Tahir Latif , Anil Goud Jegga , Sajjeev Jagannathan
Blood 124 ( 21) 3415 -3415

2014
Novel Therapeutic Strategies to Target Protein Quality Control Compartments in Multiple Myeloma

Mohamed A.Y. Abdel Malek , Sajjeev Jagannathan , Ehsan Malek , Nikhil Vad
Blood 124 ( 21) 3433 -3433

2014
Metformin Suppresses the GRP78-Dependent Delivery of Aggresomes to Autophagosomes to Enhance the Anti-Myeloma Benefit of Proteasome Inhibition

Sajjeev Jagannathan , Nikhil Vad , Mohamed A.Y. Abdel Malek , Ehsan Malek
Blood 124 ( 21) 433 -433

2014
Microrna-29b Targets PSME4 to Inhibit Proteasome Activity and Prevent the Delivery of Aggresomes to Autophagosomes for Anti-Myeloma Benefit

Sajjeev Jagannathan , Nikhil Vad , Mohamed A.Y. Abdel Malek , Ehsan Malek
Blood 124 ( 21) 4703 -4703

2014
689 ATRC-101 Drives Potent Single-Agent Activity in Mouse Syngeneic Tumor Models via a Novel Cellular Mechanism of Action

Yvonne Leung , Nikhil Vad , Anne Ye , Daniel Santos
Journal for ImmunoTherapy of Cancer 8

2020
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101

Alexander Scholz , Jeff DeFalco , Yvonne Leung , Iraz T Aydin
Proceedings of the National Academy of Sciences 119 ( 19) e2123483119

1
2022