Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration

Amanda M Travis , Samiya Manocha , Jason R Willer , Timothy S Wessler
Elife 12 e80533 -e80533

4
2023
Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration

Amanda M Travis , Samiya Manocha , Jason R Willer , Timothy S Wessler
bioRxiv 2022.05. 02.490367 -2022.05. 02.490367

1
2022
A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination.

Timothy Wessler , Louis R Joslyn , H Jacob Borish , Hannah P Gideon
PLOS Computational Biology 16 ( 5)

6
2020
Data-Driven Model Validation Across Dimensions.

Marissa Renardy , Timothy Wessler , Silvia Blemker , Jennifer Linderman
Bulletin of Mathematical Biology 81 ( 6) 1853 -1866

4
2019
Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology.

Joseph M. Cicchese , Stephanie Evans , Caitlin Hult , Louis R. Joslyn
Immunological Reviews 285 ( 1) 147 -167

151
2018
Modeling Barrier Properties of Intestinal Mucus Reinforced with IgG and Secretory IgA against Motile Bacteria.

Feifei Xu , Jay M. Newby , Jennifer L. Schiller , Holly A. Schroeder
ACS Infectious Diseases 5 ( 9) 1570 -1580

4
2019
A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors.

Jay Newby , Jennifer L. Schiller , Timothy Wessler , Jasmine Edelstein
Nature Communications 8 ( 1) 833 -833

13
2017
Modeling the Excess Cell Surface Stored in a Complex Morphology of Bleb-Like Protrusions.

Maryna Kapustina , Denis Tsygankov , Jia Zhao , Timothy Wessler
PLOS Computational Biology 12 ( 3) 1004841

23
2016
Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus.

Timothy Wessler , Alex Chen , Scott A. McKinley , Richard Cone
ACS Infectious Diseases 2 ( 1) 82 -92

18
2016
Overcoming anti-PEG antibody mediated accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG.

Morgan D. McSweeney , Lauren S.L. Price , Timothy Wessler , Elizabeth C. Ciociola
Journal of Controlled Release 1 138 -146

12
2019
An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens

Bruna Menezes , Cornelius Cilliers , Timothy Wessler , Greg M. Thurber
Aaps Journal 22 ( 2) 29

3
2020
Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection

Alexander Chen , Timothy Wessler , Katherine Daftari , Kameryn Hinton
Biophysical Journal 121 ( 9) 1619 -1631

9
2022
Antibody protection from SARS-CoV-2 respiratory tract exposure and infection

Alex Chen , Timothy Wessler , M Gregory Forest
Journal of Theoretical Biology 557 111334 -111334

8
2023
7
2023
A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes

Anne M Talkington , Morgan D McSweeney , Timothy Wessler , Marielle K Rath
Journal of Controlled Release 343 518 -527

6
2022
Optimized crosslinkers for trapping a target on a substrate

Samuel Lai , M Gregory Forest , Christine Henry , Timothy Wessler

6
2020
Experimental data and PBPK modeling quantify antibody interference in PEGylated drug carrier delivery

Anne M Talkington , Timothy Wessler , Samuel K Lai , Yanguang Cao
Bulletin of Mathematical Biology 83 ( 12) 123 -123

4
2021
Modeling predicts mechanisms altered by mutations of the SARS-CoV-2 delta and omicron variants

Jason Pearson , Timothy Wessler , Alex Chen , Richard C Boucher
bioRxiv 2022.02. 23.481492 -2022.02. 23.481492

3
2022
Computational Modeling Insights into Extreme Heterogeneity in COVID-19 Nasal Swab Data

Leyi Zhang , Han Cao , Karen Medlin , Jason Pearson
Viruses 16 ( 1) 69 -69

2023