The synthesis of a novel Crizotinib heptamethine cyanine dye conjugate that potentiates the cytostatic and cytotoxic effects of Crizotinib in patient-derived glioblastoma cell lines.

Peter J Choi , Elizabeth Cooper , Patrick Schweder , Edward Mee
Bioorganic & Medicinal Chemistry Letters 29 ( 18) 2617 -2621

3
2019
PARP inhibitor cyanine dye conjugate with enhanced cytotoxic and antiproliferative activity in patient derived glioblastoma cell lines.

Peter J Choi , Elizabeth Cooper , Patrick Schweder , Edward Mee
Bioorganic & Medicinal Chemistry Letters 30 ( 14) 127252

1
2020
Heptamethine Cyanine Dye Mediated Drug Delivery: Hype or Hope.

Peter J Choi , Thomas I− H Park , Elizabeth Cooper , Mike Dragunow
Bioconjugate Chemistry 31 ( 7) 1724 -1739

31
2020
The use of heptamethine cyanine dyes as drug-conjugate systems in the treatment of primary and metastatic brain tumors

Elizabeth Cooper , Peter J Choi , William A Denny , Jiney Jose
Frontiers in oncology 11 654921

12
2021
Conjugation of palbociclib with MHI-148 has an increased cytotoxic effect for breast cancer cells and an altered mechanism of action

Euphemia Leung , Petr Tomek , Moana Tercel , Jóhannes Reynisson
bioRxiv 2021.11. 02.466693 -2021.11. 02.466693

2021
Cytoprotective agent troxipide-cyanine dye conjugate with cytotoxic and antiproliferative activity in patient-derived glioblastoma cell lines

Elizabeth Cooper , Peter J Choi , Patrick Schweder , Edward Mee
Bioorganic & Medicinal Chemistry Letters 50 128336 -128336

7
2021
Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue

Elizabeth Cooper , Zoe Woolf , Molly EV Swanson , Jason Correia
Neuro-Oncology Advances 4 ( 1) vdac166 -vdac166

5
2022
4
2023
Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate

Elizabeth Cooper , Caitlin RM Oyagawa , Rebecca Johnson , Peter J Choi
Cell Communication and Signaling 22 ( 1) 30 -30

1
2024
The synthesis of drug-dye conjugates using pre-established tyrosine kinase inhibitors and tumour-selective Heptamethine Cyanine Dyes for the treatment of glioblastoma

Anna Cullen , Elizabeth Cooper , William A Denny , Mike Dragunow
Brain Tumor Research and Treatment 10 ( Suppl)

1
2022
CCDC 2105642: Experimental Crystal Structure Determination

Anna Cullen , Jiney Jose , Elizabeth Cooper , In Park

2021
Conjugation of Palbociclib with MHI-148 has an increased cytotoxic effect for breast cancer cells and an altered mechanism of action

Peter Jaein Choi , Petr Tomek , Moana Tercel , Jóhannes Reynisson
Molecules 27 ( 3) 880 -880

6
2022
The development of a potent, tumour-specific heptamethine cyanine dye-crizotinib conjugate for the treatment of glioblastoma

Elizabeth Alexandra Cooper , Peter J Choi , Kyung Mi Nam , Patrick Schweder
Brain Tumor Research and Treatment 10 ( Suppl)

2022
Multidimensional neuronal mechanisms drive glioblastoma cell invasion

Varun Venkataramani , Yvonne Yang , Marc Schubert , Svenja Tetzlaff
Brain Tumor Research and Treatment 10 ( Suppl)

2022
Novel synthetic approach for accessing drug–dye conjugates for targeted tumour therapy

Peter J Choi , Elizabeth A Cooper , Thomas I-H Park , William A Denny
Results in Chemistry 4 100343 -100343

3
2022