引用次数
引用: 4,117
H-指数: 36
I10-指数 : 55
出版物: 105
Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion.
John-Paul Bacik , Garrett E. Whitworth , Keith A. Stubbs , David J. Vocadlo
Chemistry & Biology 19 ( 11) 1471 -1482
74
2012
Patent 2883591 Summary
MARJOLEIN KIKKERT , BRIAN LEONARD MARK , KASTEREN VAN , PUCK BERTYNE
The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams
Tracey M. Gloster , Tracey M. Gloster , David J. Vocadlo , G. Evan Perley-Robertson
Wiley Blackwell
41
2013
Characterization of the sorbitol dehydrogenase SmoS from Sinorhizobium meliloti 1021
Ben A. Bailey-Elkin , Brian L. Mark , Ivan J. Oresnik , MacLean G. Kohlmeier
Acta Crystallographica Section D Structural Biology 77 ( 3) 380 -390
2021
Insight into a strategy for attenuating AmpC‐mediated β‐lactam resistance: Structural basis for selective inhibition of the glycoside hydrolase NagZ
Misty D. Balcewich , Keith A. Stubbs , Yuan He , Terrence W. James
Protein Science 18 ( 7) 1541 -1551
39
2009
Experimental mapping of soluble protein domains using a hierarchical approach
Jean-Denis Pedelacq , Hau B. Nguyen , Stephanie Cabantous , Brian L. Mark
Nucleic Acids Research 39 ( 18)
28
2011
Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.
Puck B. van Kasteren , Ben A. Bailey-Elkin , Terrence W. James , Dennis K. Ninaber
Proceedings of the National Academy of Sciences of the United States of America 110 ( 9) 201218464
95
2013
Synergistic activity of fosfomycin, β-lactams and peptidoglycan recycling inhibition against Pseudomonas aeruginosa.
Myriam Hamou-Segarra , Laura Zamorano , Grishma Vadlamani , Mitchell Chu
Journal of Antimicrobial Chemotherapy 72 ( 2) 448 -454
20
2017
Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein.
Egor P. Tchesnokov , Ben A. Bailey-Elkin , Brian L. Mark , Matthias Götte
PLOS Neglected Tropical Diseases 14 ( 6) 41
5
2020
Crystal Structure of the AmpR Effector Binding Domain Provides Insight into the Molecular Regulation of Inducible AmpC β-Lactamase
Misty D. Balcewich , Thomas M. Reeve , Evan A. Orlikow , Lynda J. Donald
Journal of Molecular Biology 400 ( 5) 998 -1010
41
2010
Crystallographic Structure of Human β-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of GM2 Ganglioside Hydrolysis
M. Joanne Lemieux , Brian L. Mark , Maia M. Cherney , Stephen G. Withers
Journal of Molecular Biology 359 ( 4) 913 -929
207
2006
Viral OTU Deubiquitinases: A Structural and Functional Comparison
Ben A. Bailey-Elkin , Puck B. van Kasteren , Eric J. Snijder , Marjolein Kikkert
PLoS Pathogens 10 ( 3) e1003894
20
2014
Small Molecule Inhibitors of a Glycoside Hydrolase Attenuate Inducible AmpC-mediated β-Lactam Resistance
Keith A. Stubbs , Misty Balcewich , Brian L. Mark , David J. Vocadlo
Journal of Biological Chemistry 282 ( 29) 21382 -21391
95
2007
Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression.
Ben A. Bailey-Elkin , Robert C. M. Knaap , Garrett G. Johnson , Tim J. Dalebout
Journal of Biological Chemistry 289 ( 50) 34667 -34682
142
2014
The β-Lactamase Gene Regulator AmpR Is a Tetramer That Recognizes and Binds the d-Ala-d-Ala Motif of Its Repressor UDP-N-acetylmuramic Acid (MurNAc)-pentapeptide
Grishma Vadlamani , Misty D. Thomas , Trushar R. Patel , Lynda J. Donald
Journal of Biological Chemistry 290 ( 5) 2630 -2643
43
2015
Inactivation of the Glycoside Hydrolase NagZ Attenuates Antipseudomonal β-Lactam Resistance in Pseudomonas aeruginosa
Azizah Asgarali , Keith A. Stubbs , Antonio Oliver , David J. Vocadlo
Antimicrobial Agents and Chemotherapy 53 ( 6) 2274 -2282
75
2009
AmpG Inactivation Restores Susceptibility of Pan-β-lactam Resistant Pseudomonas aeruginosa Clinical Strains
Laura Zamorano , Thomas M. Reeve , Carlos Juan , Bartolomé Moyá
Antimicrobial Agents and Chemotherapy 55 ( 5) 1990 -1996
41
2011
Structural and Biochemical Insights into the Peptidoglycan Hydrolase Domain of FlgJ from Salmonella typhimurium.
Patryk Zaloba , Ben A. Bailey-Elkin , Miriam Derksen , Brian L. Mark
PLOS ONE 11 ( 2)
12
2016
Platelet Hexosaminidase A Enzyme Assay Effectively Detects Carriers Missed by Targeted DNA Mutation Analysis
Sachiko Nakagawa , Jie Zhan , Wei Sun , Jose Carlos Ferreira
JIMD Reports 6 1 -6
4
2012
Synthesis and Use of Mechanism-Based Protein-Profiling Probes for Retaining β-d-Glucosaminidases Facilitate Identification ofPseudomonas aeruginosaNagZ
Keith A. Stubbs , Adrian Scaffidi , Aleksandra W. Debowski , Brian L. Mark
Journal of the American Chemical Society 130 ( 1) 327 -335
102
2008