Michael Spinella
机构: University of Illinois
每年引用次数
引用次数
引用: 4,173
H-指数: 35
I10-指数 : 63
出版物: 103
Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors.
Zeeshan Fazal , Michael J Spinella , Sarah J Freemantle , Ratnakar Singh
Cancers 13 ( 7) 1506
2021
Functional Characterization of the Orphan Nuclear Receptor TLX in Triple Negative Breast Cancer
David Gewirtz , Michael J Spinella , Erik Russell Nelson , Sisi He
Journal of the Endocrine Society 5
2021
Retinoic acid activates p53 in human embryonal carcinoma through retinoid receptor-dependent stimulation of p53 transactivation function.
Joshua C Curtin , Konstantin H Dragnev , David Sekula , Allison J Christie
Oncogene 20 ( 20) 2559 -2569
48
2001
Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma.
Sarah J Freemantle , Joanna S Kerley , Shannon L Olsen , Robert H Gross
Oncogene 21 ( 18) 2880 -2889
88
2002
Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells.
Kelly C Heim , Kristina A White , Dexin Deng , Craig R Tomlinson
Molecular Cancer 6 ( 1) 57 -57
24
2007
Retinoids in cancer therapy and chemoprevention: promise meets resistance
Sarah J Freemantle , Michael J Spinella , Ethan Dmitrovsky
Oncogene 22 ( 47) 7305 -7315
277
2003
p53 in human embryonal carcinoma: identification of a transferable, transcriptional repression domain in the N-terminal region of p53.
Joshua C Curtin , Michael J Spinella
Oncogene 24 ( 9) 1481 -1490
12
2005
A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embyronal carcinoma
Joanna S Kerley-Hamilton , Aimee M Pike , Na Li , James DiRenzo
Oncogene 24 ( 40) 6090 -6100
83
2005
Safety and tolerability of guadecitabine (SGI-110) plus cisplatin in patients (pts) with platinum-refractory germ cell tumors (GCT): Preliminary results from an open label phase 1b study.
Neda Hashemi-Sadraei , Lawrence H. Einhorn , Susan Perkins , Michael J Spinella
Journal of Clinical Oncology 36 ( 15_suppl) e16545 -e16545
2018
Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting
Grace E Snow , Allison C Kasper , Alexander M Busch , Elisabeth Schwarz
BMC Cancer 9 ( 1) 383 -383
26
2009
Organization of the murine reduced folate carrier gene and identification of variant splice forms
Kevin E Brigle , Michael J Spinella , Esteban E Sierra , I.David Goldman
Biochimica et Biophysica Acta 1353 ( 2) 191 -198
47
1997
4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RARγ independent pathway
Sutisak Kitareewan , Michael J Spinella , Janet Allopenna , Peter R Reczek
Oncogene 18 ( 42) 5747 -5755
48
1999
Specific retinoid receptors cooperate to signal growth suppression and maturation of human embryonal carcinoma cells
Michael J Spinella , Sutisak Kitareewan , Begonia Mellado , David Sekula
Oncogene 16 ( 26) 3471 -3480
33
1998
FGF4 dissociates anti-tumorigenic from differentiation signals of retinoic acid in human embryonal carcinomas.
Wolfgang J Maerz , Jose Baselga , Victor E Reuter , Begona Mellado
Oncogene 17 ( 6) 761 -767
25
1998
All-trans-retinoic acid antagonizes the hedgehog pathway by inducing patched
Alexander M Busch , Fabrizio Galimberti , Kristen E Nehls , Monic Roengvoraphoj
Cancer Biology & Therapy 15 ( 4) 463 -472
8
2014
Toward a mechanistic understanding of poly-and perfluoroalkylated substances and cancer
Raya I Boyd , Saeed Ahmad , Ratnakar Singh , Zeeshan Fazal
Cancers 14 ( 12) 2919
2
2022
Per-and polyfluoroalkyl substance exposure combined with high-fat diet supports prostate cancer progression
Ozan Berk Imir , Alanna Zoe Kaminsky , Qian-Ying Zuo , Yu-Jeh Liu
Nutrients 13 ( 11) 3902
7
2021
Nephrotoxicity of perfluorooctane sulfonate (PFOS)—effect on transcription and epigenetic factors
Yi Wen , Faizan Rashid , Zeeshan Fazal , Ratnakar Singh
Environmental Epigenetics 8 ( 1) dvac010
3
2022
Low-dose demethylation therapy for the treatment of cisplatin-resistant testicular cancer
Andrea Corbet , Costantine Albany , Emmanuel Bikorimana , Ema Khan
Cancer Research 78 ( 13_Supplement) 2999 -2999
2018
Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine
J Freemantle , Brock C Christensen , Lawrence H Einhorn , Michael J Spinella