Serge L. Beaucage
机构: Food and Drug Administration
每年引用次数
引用次数
引用: 15,652
H-指数: 43
I10-指数 : 93
出版物: 175
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
D. M. Klinman , A. K. Yi , S. L. Beaucage , J. Conover
Proceedings of the National Academy of Sciences of the United States of America 93 ( 7) 2879 -2883
1,979
1996
A Novel Function of RNAs Arising From the Long Terminal Repeat of Human Endogenous Retrovirus 9 in Cell Cycle Arrest
L. Xu , A. G. Elkahloun , F. Candotti , A. Grajkowski
Journal of Virology 87 ( 1) 25 -36
18
2013
Recent Developments in the Synthesis of RNA Oligonucleotides for Potential Therapeutic Applications.
J. Cieslak , A. Grajkowski , C. Ausin , S. L. Beaucage
Nucleic Acids Symposium Series 52 ( 1) 55 -56
2008
LARGE-SCALE PREPARATION OF THE SULFUR-TRANSFER REAGENT 3H-1,2-BENZODITHIOL-3-ONE 1,1-DIOXIDE
J. B. Regan , L. R. Phillips , S. L. Beaucage
Organic Preparations and Procedures International 24 ( 4) 488 -492
13
1992
Amphipathic trans-acting phosphorothioate DNA elements mediate the delivery of uncharged nucleic acid sequences in mammalian cells
H. V. Jain , D. Verthelyi , S. L. Beaucage
RSC Advances 5 ( 80) 65245 -65254
6
2015
An amphipathic trans-acting phosphorothioate RNA element delivers an uncharged phosphorodiamidate morpholino sequence in mdx mouse myotubes.
H. V. Jain , J. F. Boehler , D. Verthelyi , K. Nagaraju
RSC Advances 7 ( 67) 42519 -42528
1
2017
Innovative 2'-O-Imino-2-propanoate-Protecting Group for Effective Solid-Phase Synthesis and 2'-O-Deprotection of RNA Sequences.
Andrzej Grajkowski , Serge L. Beaucage , Mayumi Takahashi , Brian M. Cawrse
Journal of Organic Chemistry 86 ( 7) 4944 -4956
2021
An Improved PEG-Linked Solid Support for Minimizing Process-Related Impurities During Solid-Phase Synthesis of DNA and RNA Sequences.
Andrzej Grajkowski , Serge L. Beaucage , Mayumi Takahashi , Brian M. Cawrse
Current protocols 1 ( 5)
2021
The synthesis of specific ribonucleotides and unrelated phosphorylated biomolecules by the phosphoramidite method
Serge L. Beaucage , Radhakrishnan P. Iyer
Tetrahedron 49 ( 46) 10441 -10488
100
1993
Assessment of the cellular internalization of thermolytic phosphorothioate DNA oligonucleotide prodrugs
Harsh V. Jain , Kazuyo Takeda , Cecilia Tami , Daniela Verthelyi
Bioorganic & Medicinal Chemistry 21 ( 20) 6224 -6232
11
2013
Protection of the 2′-Hydroxy Function of Ribonucleosides as an Iminooxymethyl Propanoate and Its 2′-O-Deprotection through an Intramolecular Decarboxylative Elimination Process
Jacek Cieślak , Andrzej Grajkowski , Cristina Ausín , Serge L. Beaucage
European Journal of Organic Chemistry 2016 ( 35) 5817 -5821
2
2016
The synthesis of oligoribonucleotides. II. The use of silyl protecting groups in nucleoside and nucleotide chemistry. VII
Kelvin K. Ogilvie , Serge L. Beaucage , Aria L. Schifman , Nicole Y. Theriault
Canadian Journal of Chemistry 56 ( 17) 2230 -2238
215
1978
Attachment of Reporter and Conjugate Groups to DNA
Serge L. Beaucage
ChemInform 32 ( 1)
1
2001
Convenient Synthesis of a Propargylated Cyclic (3′-5′) Diguanylic Acid and Its “Click” Conjugation to a Biotinylated Azide
Andrzej Grajkowski , Jacek Cieślak , Alexei Gapeev , Christian Schindler
Bioconjugate Chemistry 21 ( 11) 2147 -2152
29
2010
Thermolytic release of covalently linked DNA oligonucleotides and their conjugates from controlled-pore glass at near neutral pH.
Andrzej Grajkowski , Jacek Cieślak , Jon S. Kauffman , Robert J. Duff
Bioconjugate Chemistry 19 ( 8) 1696 -1706
20
2008
The automated synthesis of sulfur-containing oligodeoxyribonucleotides using 3H-1,2-benzodithiol-3-one 1,1-dioxide as a sulfur-transfer reagent
Radhakrishnan P. Iyer , Lawrence R. Phillips , William Egan , Judith B. Regan
Journal of Organic Chemistry 55 ( 15) 4693 -4699
275
1990
Synthetic Strategies and Parameters Involved in the Synthesis of Oligodeoxyribonucleotides According to the Phosphoramidite Method
Serge L. Beaucage , Marvin H. Caruthers
Current protocols in human genetics ( 1)
30
2000
2′‐Hydroxy Protection of Ribonucleosides as 2‐Cyano‐2,2‐Dimethylethanimine‐N‐Oxymethyl Ethers in Solid‐Phase Synthesis of RNA Sequences
Jacek Cieślak , Cristina Ausín , Andrzej Grajkowski , Serge L. Beaucage
Current protocols in human genetics 54 ( 1)
2013
The 4‐Methylthio‐1‐Butyl Group for Phosphate/Thiophosphate Protection in Oligodeoxyribonucleotide Synthesis
Jacek Cieślak , Andrzej Grajkowski , Victor Livengood , Serge L. Beaucage
Current protocols in human genetics 19 ( 1)
2004
Protection of Nucleosides for Oligonucleotide Synthesis
Serge L. Beaucage
Current protocols in human genetics 16 ( 1)
2004