引用次数
引用: 9,589
H-指数: 55
I10-指数 : 167
出版物: 213
11C-Glycylsarcocine targeting the peptide transporter as a novel PET imaging tracer for cancer detection
Sosuke Miyoshi , Yoshiyuki Kubo , Akira Tsuji , Akihiro Noda
Society of Nuclear Medicine Annual Meeting Abstracts 49
2008
Biliary excretion mechanism of CPT-11 and its metabolites in humans: involvement of primary active transporters.
Ritchie Froehlich , Carol E. Green , Jack E. Dabbs , Valorie Weizer
Cancer Research 58 ( 22) 5137 -5143
114
1998
Methotrexate Is Excreted into the Bile by Canalicular Multispecific Organic Anion Transporter in Rats
Yuichi Sugiyama , Kayoko Ni'inuma , Ryuichiro Nishigaki , Masayo Yamazaki
Cancer Research 57 ( 16) 3506 -3510
162
1997
Selective Inhibition of Human Cytochrome P450 3A4 byN-[2(R)-Hydroxy-1(S)-indanyl]-5-[2(S)-(1,1-dimethylethylaminocarbonyl)-4-[(furo[2,3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethylpentanamide and P-glycoprotein by Valspodar in Gene Transfectant Systems
Yuichi Sugiyama , Hiroshi Suzuki , Charles L. Crespi , Kiyomi Ito
Drug Metabolism and Disposition 28 ( 10) 1238 -1243
22
2000
Active Efflux of CPT-11 and Its Metabolites in Human KB-Derived Cell Lines
Yuichi Sugiyama , Xiao-Yan Chu , Hiroshi Suzuki , Yukio Kato
Journal of Pharmacology and Experimental Therapeutics 288 ( 2) 735 -741
82
1999
Possible involvement of P-glycoprotein in biliary excretion of CPT-11 in rats.
Yuichi Sugiyama , Xiao-Yan Chu , Yukio Kato
Drug Metabolism and Disposition 27 ( 4) 440 -441
44
1999
Pharmacokinetics of Erythropoietin in Genetically Anemic Mice
Hiroshi Kamiyama , Kumi Miura , Yukio Kato , Akira Okazaki
Drug Metabolism and Disposition 26 ( 2) 126 -131
26
1998
Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan.
Yuichi Sugiyama , Takashi Igarashi , Yukio Kato , Akiko Nishino
Drug Metabolism and Disposition 28 ( 10) 1146 -1148
40
2000
Multiplicity of biliary excretion mechanisms for irinotecan, CPT-11, and its metabolites in rats.
Yuichi Sugiyama , Xiao-Yan Chu , Yukio Kato
Cancer Research 57 ( 10) 1934 -1938
122
1997
Multispecific Organic Anion Transporter Is Responsible for the Biliary Excretion of the Camptothecin Derivative Irinotecan and its Metabolites in Rats
Yuichi Sugiyama , Kayoko Niinuma , Xiao-Yan Chu , Yukio Kato
Journal of Pharmacology and Experimental Therapeutics 281 ( 1) 304 -314
153
1997
Stereoselective Hepatobiliary Transport of the Quinolone Antibiotic Grepafloxacin and Its Glucuronide in the Rat
Yuichi Sugiyama , Akira Tsuji , Yukio Kato , Hiroyuki Sasabe
Journal of Pharmacology and Experimental Therapeutics 284 ( 2) 661 -668
16
1998
Efficient Extraction by the Liver Governs Overall Elimination of Hepatocyte Growth Factor in Rats
Yuichi Sugiyama , Motohiro Kato , Toshikazu Nakamura , Yukio Kato
Journal of Pharmacology and Experimental Therapeutics 290 ( 1) 373 -379
10
1999
Hydroxyprolylserine derivatives JBP923 and JBP485 exhibit the antihepatitis activities after gastrointestinal absorption in rats.
Yuichi Sugiyama , Tai-Ichi Kaku , Tomofumi Santa , Takashi Ishizu
Journal of Pharmacology and Experimental Therapeutics 294 ( 2) 510 -515
75
2000
Nonlinear Disposition Kinetics of a Novel Antifolate, MX-68, in Rats
Yuichi Sugiyama , Yukio Kato , Yong-Hae Han
Journal of Pharmacology and Experimental Therapeutics 291 ( 1) 204 -212
9
1999
Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide.
Yuichi Sugiyama , Kayoko Niinuma , Toru Horie , Hiroshi Suzuki
Journal of Pharmacology and Experimental Therapeutics 282 ( 2) 866 -872
49
1997
Inhibition of biliary excretion of methotrexate by probenecid in rats: quantitative prediction of interaction from in vitro data.
Yuichi Sugiyama , Yukio Kato , Kanji Komatsu , Kaoru Ueda
Journal of Pharmacology and Experimental Therapeutics 297 ( 3) 1036 -1043
47
2001
Characterization of novel kidney-specific delivery system using an alkylglucoside vector.
Yuichi Sugiyama , Kazuhiko Shirota , Koukichi Suzuki , Yukio Kato
Journal of Pharmacology and Experimental Therapeutics 299 ( 2) 459 -467
21
2001
Involvement of an Organic Anion Transporter (Canalicular Multispecific Organic Anion Transporter/Multidrug Resistance-Associated Protein 2) in Gastrointestinal Secretion of Glutathione Conjugates in Rats
Yuichi Sugiyama , Hiroshi Suzuki , Setsuo Kinoshita , Yasumasa Gotoh
Journal of Pharmacology and Experimental Therapeutics 292 ( 1) 433 -439
134
2000
Mechanism for the Nonlinear Pharmacokinetics of Erythropoietin in Rats
Yuichi Sugiyama , Hiroshi Kamiyama , Akira Okazaki , Kenji Kumaki
Journal of Pharmacology and Experimental Therapeutics 283 ( 2) 520 -527
72
1997
Hepatobiliary Transport Governs Overall Elimination of Peptidic Endothelin Antagonists in Rats
Sharif Akhteruzzaman , Akihiro Hisaka , Yuichi Sugiyama , Yukio Kato
Journal of Pharmacology and Experimental Therapeutics 288 ( 2) 568 -574
12
1999