Mark Sliwkowski
机构: Distinguished Staff Scientist (Genentech, retired). Denali Therapeutics
每年引用次数
引用次数
引用: 47,542
H-指数: 84
I10-指数 : 187
出版物: 346
anticorpo, ácido nucleico, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, métodos de tratamento, de inibição da proliferação de uma célula e de detecção de her2 humana e método para a detecção de um câncer
Mark Dennis , Xiaocheng Chen , Gail Lewis Phillips , Jagath Reddy Junutula
2018
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth.
David B Agus , Robert W Akita , William D Fox , Gail D Lewis
Cancer Cell 2 ( 2) 127 -137
775
2002
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
Matthew C Franklin , Kendall D Carey , Felix F Vajdos , Daniel J Leahy
Cancer Cell 5 ( 4) 317 -328
1,313
2004
Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.
Zuleima Aguilar , Robert W Akita , Richard S Finn , B Lillian Ramos
Oncogene 18 ( 44) 6050 -6062
138
1999
γ-Heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175
Gabriele Schaefer , V Danial Fitzpatrick , Mark X Sliwkowski
Oncogene 15 ( 12) 1385 -1394
124
1997
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index
Jagath R Junutula , Helga Raab , Suzanna Clark , Sunil Bhakta
Nature Biotechnology 26 ( 8) 925 -932
1,278
2008
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
Ben-Quan Shen , Keyang Xu , Luna Liu , Helga Raab
Nature Biotechnology 30 ( 2) 184 -189
933
2012
Neuregulin receptor-mediated gene transfer by human epidermal growth factor receptor 2-targeted antibodies and neuregulin-1.
Jeffrey A Kern , Robert Wakita , Mark X Sliwkowski
Cancer Gene Therapy 6 ( 6) 537 -545
2
1999
Regulation of the acetylcholine receptor ϵ subunit gene by recombinant ARIA: An in vitro model for transynaptic gene regulation
Gerald C Chu , Lisa M Moscoso , Mark X Sliwkowski , John P Merlie
Neuron 14 ( 2) 329 -339
123
1995
Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4
V.Danial Fitzpatrick , Paul I Pisacane , Richard L Vandlen , Mark X Sliwkowski
FEBS Letters 431 ( 1) 102 -106
81
1998
Binding specificities and affinities of egf domains for ErbB receptors.
Jennifer T Jones , Robert W Akita , Mark X Sliwkowski
FEBS Letters 447 ( 2) 227 -231
327
1999
An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors
Antony W Burgess , Hyun-Soo Cho , Charles Eigenbrot , Kathryn M Ferguson
Molecular Cell 12 ( 3) 541 -552
756
2003
Heregulin variants
Marcus D Ballinger , Jennifer T Jones , Wayne J Fairbrother , Mark X Sliwkowski
36
2002
Heregulin variants
Marcus D Ballinger , Jennifer T Jones , Wayne J Fairbrother , Mark X Sliwkowski
34
2000
Heregulin variants
Marcus D Ballinger , Jennifer T Jones , Wayne J Fairbrother , Mark X Sliwkowski
18
2006
Dual targeting of HER2-positive cancer with trastuzumab-emtansine (T-DM1) and pertuzumab: critical role for neuregulin blockade in anti-tumor response to combination therapy
Gail D Lewis Phillips , Carter T Fields , Guangmin Li , Donald Dowbenko
Author and Subject Index Vol. 63, Suppl. 1, 2002
Axel Ullrich , Marc van de Vijver , José Baselga , Lisa A Hammond
Oncology 63 ( Suppl. 1) 64 -64
2002
Targeting HERZ: Recent Developments and Future Directions for Breast Cancer Patients
Robert W Akita , Carlos L Arteaga , Gabriel N Hortobagyi , Mien-Chie Hung
Oncogenic ERBB3 Mutations in Human Cancers (vol 23, pg 603, 2013)
Bijay S Jaiswal , Noelyn M Kljavin , Eric W Stawiski , Emily Chan
CANCER CELL 25 ( 4) 543 -544
1
2014
Afucosylated Antibodies Increase Activation of FcgRIIIa-Dependent Signaling Components to Intensify Processes Promoting ADCC
Scot D Liu , Cecile Chalouni , Judy C Young , Teemu T Junttila