引用次数
引用: 341
H-指数: 5
I10-指数 : 5
出版物: 21
Reactivation of cAMP Pathway by PDE4D Inhibition Represents a Novel Druggable Axis for Overcoming Tamoxifen Resistance in ER-positive Breast Cancer
Rasmi R Mishra , Nevin Belder , Suhail A Ansari , Merve Kayhan
Clinical Cancer Research 24 ( 8) 1987 -2001
13
2018
TLR ligand loaded exosome mediated immunotherapy of established mammary Tumor in mice
Muzaffer Yildirim , Tugce Canavar Yildirim , Nilsu Turay , Tugce Bildik
Immunology Letters 239 32 -41
6
2021
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin
Marco Biondini , Alex Kiepas , Leeanna El-Houjeiri , Matthew G Annis
Oncogene 41 ( 12) 1701 -1717
13
2022
Targeting PDE4D reinstates toxic PARP trapping via cAMP-ROS-DNA damage axis and restores the efficacy of standard of care in treatment-refractory ER+ breast cancer
Ozge Saatci , Metin Cetin , Meral Uner , Unal M Tokat
Cancer Research 84 ( 6_Supplement) 563 -563
2024
Exceptional Response to MEK Inhibition in a Patient With RAF1-Mutant Myxofibrosarcoma: Case Report and Mechanistic Overview
Eylül Özgü , Esranur Aydin , Ashkan Adibi , Ünal Metin Tokat
JCO Precision Oncology 7 e2300299 -e2300299
1
2023
Navigating uncharted territory: a case report and literature review on the remarkable response to personalized crizotinib containing combinational therapy in a pazopanib refractory patient with novel alterations
Esranur Aydın , Ünal Metin Tokat , Eylül Özgü , Ashkan Adibi
Therapeutic Advances in Medical Oncology 16 17588359241247023 -17588359241247023
2024
PARP inhibitor combinations with high-dose vitamin C in the treatment of Ewing sarcoma: two case reports and mechanistic overview
Ashkan Adibi , Ünal Metin Tokat , Eylül Özgü , Esranur Aydın
Therapeutic Advances in Medical Oncology 15 17588359231213841 -17588359231213841
2
2023
Durable radiologic and molecular complete response following nivolumab in an HNSCC patient with UV signature and HIV
Ashkan Adibi , Ünal Metin Tokat , Eylül Özgü , Nurseit Mamyrov
Oral Oncology 154 106859 -106859
2024
Therapeutic vulnerabilities and pan-cancer landscape of BRAF class III mutations in epithelial solid tumors
Eylül Özgü , Benjamin G Kaplan , Smruthy Sivakumar , Ethan S Sokol
BJC reports 2 ( 1) 77 -77
2024
Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer. Nat Commun. 2020; 11: 2416
O Saatci , A Kaymak , U Raza , PG Ersan
5
Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer
Ozge Saatci , Aysegul Kaymak , Umar Raza , Pelin G Ersan
Nature Communications 11 ( 1) 2416
118
2020
Competing endogenous RNA (ceRNAs) interaction network regulating lung metastasis in triple negative breast cancer
Pelin Gulizar Ersan , Unal Metin Tokat , Erol Eyupoglu , Umar Raza
2017
Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer
Ridho Assidicky , Unal Metin Tokat , Ibrahim Oguzhan Tarman , Ozge Saatci
Breast Cancer Research and Treatment 193 ( 2) 331 -348
24
2022
Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer
Ozge Saatci , Rashedul Alam , Kim-Tuyen Huynh-Dam , Aynur Isik
Cell Death & Disease 15 ( 6) 418 -418
1
2024
Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer
Ozge Saatci , Metin Cetin , Meral Uner , Unal Metin Tokat
Nature Communications 14 ( 1) 6997 -6997
1
2023
Abstract PO4-23-10: Restoring the efficacy of standard of care in treatment-refractory ER+ breast cancer by re-activation of cAMP-ROS-DNA damage axis
Ozge Saatci , Metin Cetin , Meral Uner , Unal Metin Tokat
Cancer Research 84 ( 9_Supplement) PO4 -PO4
2024
Abstract A008: Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer
Ozge Saatci , Mein Cetin , Meral Uner , Unal Metin Tokat
Cancer Research 84 ( 1_Supplement) A008 -A008
2024
Overcoming tamoxifen resistance by re-activating cAMP-Ca2+− ROS-ferroptosis axis in ER+ breast cancer
Rashedul Alam , Ozge Saatci , Meral Bugadyci Uner , Kim-Tuyen Huynh-Dam
Cancer Research 83 ( 7_Supplement) 3883 -3883
2023
Overcoming tamoxifen resistance and inhibiting metastatic recurrence in estrogen receptor-positive breast cancer
Pelin Gulizar Ersan , Ozge Saatci , Oguzhan Tarman , Rasmi Mishra
Cancer Research 79 ( 13_Supplement) 2121 -2121
2019
Evaluation of the Relationship between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells
Yasemin Kartal , Unal Metin Tokat , Pelin Kelicen-Ugur , Serkan Yılmaz
Current molecular pharmacology 16 ( 6) 609 -628
2023