iRHOM2 is a critical pathogenic mediator of inflammatory arthritis
Lionel B. Ivashkiv , Tak W. Mak , Jane E. Salmon , Carl P. Blobel
Journal of Clinical Investigation 123 ( 2) 928 -932
179
2013
iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling
Xue Li , Thorsten Maretzky , Gisela Weskamp , Sébastien Monette
Proceedings of the National Academy of Sciences of the United States of America 112 ( 19) 6080 -6085
87
2015
The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner.
Carl P Blobel , Thorsten Maretzky , Priya D Issuree , Joseph Skurski
Frontiers in Cellular and Infection Microbiology 10 620392 -620392
1
2021
Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages
MacLean Sellars , Jun R Huh , Kenneth Day , Priya D Issuree
Nature Immunology 16 ( 7) 746 -754
55
2015
FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways
Garima Dixit , Jesus Gonzalez‐Bosquet , Joseph Skurski , Eric J Devor
Clinical and translational medicine 13 ( 5) e1223 -e1223
2
2023
CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element
Athmane Teghanemt , Priyanjali Pulipati , Kara Misel-Wuchter , Kenneth Day
Nature communications 13 ( 1) 1477 -1477
6
2022
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation
Athmane Teghanemt , Kara Misel‐Wuchter , Jace Heath , Andrew Thurman
EMBO reports 24 ( 5) e55543 -e55543
2
2023
Neuronal IL-17 controls C. elegans developmental diapause through CEP-1/p53
Abhishiktha Godthi , Sehee Min , Srijit Das , Johnny Cruz-Corchado
BioRxiv 2022.11. 22.517560 -2022.11. 22.517560
2
2022
Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53
Abhishiktha Godthi , Sehee Min , Srijit Das , Johnny Cruz-Corchado
Proceedings of the National Academy of Sciences 121 ( 12) e2315248121 -e2315248121
2024
DNA demethylation fine-tunes IL-2 production during thymic development and promotes Regulatory T cell differentiation
Priya D Issuree , Athmane Teghanemt , Jace Heath , Andrew Thurman
The Journal of Immunology 210 ( 1_Supplement) 76.24 -76.24
2023
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding
T. Maretzky , D. R. McIlwain , P. D. A. Issuree , X. Li
Proceedings of the National Academy of Sciences of the United States of America 110 ( 28) 11433 -11438
166
2013
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.
S. M. Le Gall , T. Maretzky , P. D. A. Issuree , X.-D. Niu
Journal of Cell Science 123 ( 22) 3913 -3922
149
2010
Resveratrol attenuates C5a-induced inflammatory responses in vitro and in vivo by inhibiting phospholipase D and sphingosine kinase activities
Priya D. A. Issuree , Peter N. Pushparaj , Shazib Pervaiz , Alirio J. Melendez
The FASEB Journal 23 ( 8) 2412 -2424
47
2009
Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice
Priya D. A. Issuree , Charles P. Ng , Dan R. Littman
Frontiers in Immunology 8 291
18
2017
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding (vol 110, pg 11433, 2013)
Thorsten Maretzky , David R McIlwain , Priya Darshinee A Issuree , Xue Li
Proceedings of the National Academy of Sciences-PNAS 118 ( 34)
2021
iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Xiaoping Qing , Lindsay D. Rogers , Arthur Mortha , Yonit Lavin
European Journal of Immunology 46 ( 12) 2737 -2748
17
2016
Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.
Priya D. Issuree , Kenneth Day , Christy Au , Ramya Raviram
Nature Communications 9 ( 1) 3594
13
2018
Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation.
Joseph Skurski , Christie M. Penniman , Ramasatyaveni Geesala , Garima Dixit
Metabolism-clinical and Experimental 106 154194
16
2020
iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling
Xiaoping Qing , Yurii Chinenov , Patricia Redecha , Michael Madaio
Journal of Clinical Investigation 128 ( 4) 1397 -1412
73
2018
Loss of RHBDF2 results in an early-onset spontaneous murine colitis.
Ramasatyaveni Geesala , Willow Schanz , Mikayla Biggs , Garima Dixit
Journal of Leukocyte Biology 105 ( 4) 767 -781
14
2019