Jukka Westermarck
机构: Professor of cancer biology
每年引用次数
引用次数
引用: 13,323
H-指数: 55
I10-指数 : 96
出版物: 117
Mechanisms of MYC stabilization in human malignancies
Melissa R JUNTTILA , Jukka WESTERMARCK
Cell cycle 8 ( 3) 507 -507
2009
OKADAIC ACID DOWN-REGULATES ELASTIN GENE-EXPRESSION BY HUMAN SKIN FIBROBLASTS IN CULTURE
VM KAHARI , J WESTERMARCK
JOURNAL OF INVESTIGATIVE DERMATOLOGY 103 ( 3) 415 -415
1994
Activation of Fibroblast Collagenase-1 Expression by Tumor Cells of Squamous Cell Carcinomas Is Mediated by p38 Mitogen-activated Protein Kinase and c-Jun NH2-terminal Kinase-2
Jukka Westermarck , Songping Li , Panu Jaakkola , Tuula Kallunki
Cancer Research 60 ( 24) 7156 -7162
44
2000
Discovery of a Novel CIP2A Variant (NOCIVA) with clinical relevance in predicting TKI resistance in myeloid leukemias
Tea Ammunét , Eliisa Löyttyniemi , Veli-Matti Kähäri , Laura L Elo
Clinical Cancer Research 27 ( 10) 2848 -2860
2021
Druggable cancer phosphatases.
Jukka Westermarck , Jukka Westermarck , Julia P. Vainonen , Majid Momeny
Science Translational Medicine 13 ( 588)
51
2021
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Jukka Westermarck , Jukka Westermarck , Andrea Newbold , Andrea Newbold
Cell
58
2021
Circumventing Drug Treatment? Intrinsic Lethal Effects of Polyethyleneimine (PEI)-Functionalized Nanoparticles on Glioblastoma Cells Cultured in Stem Cell Conditions.
Markus Peurla , Jukka Westermarck , Jessica M. Rosenholm , Eudald Casals
Cancers 13 ( 11) 2631
2021
c-Jun Supports Ribosomal RNA Processing and Nucleolar Localization of RNA Helicase DDX21
Tim H. Holmström , Antoine Mialon , Marko Kallio , Yvonne Nymalm
Journal of Biological Chemistry 283 ( 11) 7046 -7053
37
2008
ETS1 Mediates MEK1/2-Dependent Overexpression of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Human Cancer Cells
Anchit Khanna , Juha Okkeri , Turker Bilgen , Timo Tiirikka
PLoS ONE 6 ( 3) e17979
83
2011
MYC is not detected in highly proliferating normal spermatogonia but is coupled with CIP2A in testicular cancers
Sami Ventelä , Juho-Antti Mäkelä , Rosalie Sears , Jorma Toppari
Matters (Zürich) 2 ( 3) 1 -1
1
2016
Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1
Otto Kauko , Susumu Y. Imanishi , Evgeny Kulesskiy , Laxman Yetukuri
Journal of Biological Chemistry 295 ( 13) 4194 -4211
38
2020
Integrated network analysis platform for protein-protein interactions
Jianmin Wu , Tea Vallenius , Kristian Ovaska , Jukka Westermarck
Nature Methods 6 ( 1) 75 -77
346
2009
CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling.
Mohd Moin Khan , Ubaid Ullah , Meraj H Khan , Lingjia Kong
iScience 23 ( 3) 100947
7
2020
KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo
Pirita Pekkonen , Annika Järviluoma , Nadezhda Zinovkina , Anna Cvrljevic
Cell Cycle 13 ( 23) 3670 -3684
11
2014
Regulation of protein phosphatase 2A (PP2A) tumor suppressor function by PME-1.
Amanpreet Kaur , Jukka Westermarck
Biochemical Society Transactions 44 ( 6) 1683 -1693
30
2016
Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer.
Amanpreet Kaur , Adam Elzagheid , Eva‐Maria Birkman , Tuulia Avoranta
Cancer Medicine 4 ( 12) 1798 -1808
18
2015
Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.
Caitlin M. O’Connor , Daniel Leonard , Danica Wiredja , Rita A. Avelar
Oncogene 39 ( 3) 703 -717
12
2020
Regulation of matrix metalloproteinase expression in tumor invasion
Jukka Westermarck , Veli‐Matti Kähäri
The FASEB Journal 13 ( 8) 781 -792
2,087
1999
Optimized design and analysis of preclinical intervention studies in vivo
Teemu D Laajala , Mikael Jumppanen , Riikka Huhtaniemi , Vidal Fey
Scientific Reports 6 ( 1) 30723 -30723
39
2016
CIP2A increases self-renewal and is linked to Myc in neural progenitor cells
Laura Kerosuo , Heli Fox , Nina Perälä , Kati Ahlqvist
Differentiation 80 ( 1) 68 -77
30
2010