Martin Renatus
机构: Associate Director, Novartis Pharma
每年引用次数
引用次数
引用: 7,812
H-指数: 31
I10-指数 : 41
出版物: 69
Regulation of caspase-9 activity revealed at the atomic level.
M Renatus , SJ Riedl , FL Scott , H Shin
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 224 U81 -U81
2002
An allosteric MALT1 inhibitor as a molecular corrector for protein function rescuing in an immunodeficient patient
SY Fung , J Quancard , T Klein , M Renatus
EUROPEAN JOURNAL OF IMMUNOLOGY 49 1222 -1223
2019
Protein TAILS tell remarkable tales: N-terminomics reveals the proteolytic landscape of immunity
C Overall , J Quancard , T Klein , S Fung
FEBS OPEN BIO 8 72 -72
2018
Screening for inhibitors of the ubiquitination regulator and anti-cancer target CSN5 using a HTS fluorescence polarization method
U Hassiepen , MD Jones , R Assenberg , I Bechtold
Online Commentary
S Vainio , I Bykov , M Hermansson , E Jokitalo
Biochemical Journal 391 ( part 3)
2005
A first-in-class small molecule inhibitor of the COP9 signalosome subunit 5 for the treatment of cancer
Ulrich Hassiepen , Michael Kiffe , Jean Quancard , Richard Sedrani
Nature Publishing
2016
Crystal structure of the apoptotic suppressor CrmA in its cleaved form
Martin Renatus , Qiao Zhou , Henning R Stennicke , Scott J Snipas
Structure 8 ( 7) 789 -797
50
2000
Structural Determinants of MALT1 Protease Activity
Christian Wiesmann , Lukas Leder , Jutta Blank , Anna Bernardi
Journal of Molecular Biology 419 ( 1-2) 4 -21
61
2012
N-aryl-piperidine-4-carboxamides as a novel class of potent inhibitors of MALT1 proteolytic activity
Achim Schlapbach , Laszlo Revesz , Carole Pissot Soldermann , Thomas Zoller
Bioorganic & Medicinal Chemistry Letters 28 ( 12) 2153 -2158
11
2018
Mechanism-based inactivation of caspases by the apoptotic suppressor p35.
Stefan J. Riedl , Martin Renatus , Scott J. Snipas , Guy S. Salvesen
Biochemistry 40 ( 44) 13274 -13280
34
2001
156 Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single chain human tPA and vampire bat plasminogen activator
Martin Renatus , Richard A. Engh , Milton T. Stubbs , Robert Huber
Fibrinolysis and Proteolysis 11 44
1997
157 The “activation domain”: A highly cooperative entity within the catalytic domain of serine proteinases
Wolfram Bode , Doriano Lamba , Martin Renatus , Richard Engh
Fibrinolysis and Proteolysis 11 45
1997
Structural Basis for the Inhibition of Caspase-3 by XIAP
Stefan J. Riedl , Martin Renatus , Robert Schwarzenbacher , Qiao Zhou
Cell 104 ( 5) 791 -800
1,059
2001
Ubiquitin Specific Protease 2
Martin Renatus , Ulrich Hassiepen
Handbook of Proteolytic Enzymes 2066 -2070
2013
XIAP inhibits caspase‐3 and ‐7 using two binding sites: evolutionarily conserved mechanism of IAPs
Fiona L Scott , Jean-Bernard Denault , Stefan J Riedl , Hwain Shin
The EMBO Journal 24 ( 3) 645 -655
301
2005
The crystal structure of caspase-6, a selective effector of axonal degeneration
Renato Baumgartner , Gabriele Meder , Christophe Briand , Arnaud Decock
Biochemical Journal 423 ( 3) 429 -439
45
2009
The T‐cell fingerprint of MALT1 paracaspase revealed by selective inhibition
Maureen Bardet , Adeline Unterreiner , Claire Malinverni , Frédérique Lafossas
Immunology and Cell Biology 96 ( 1) 81 -99
33
2018
Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus
Paul Erbel , Nikolaus Schiering , Allan D'Arcy , Martin Renatus
Nature Structural & Molecular Biology 13 ( 4) 372 -373
377
2006
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
Achim Schlapbach , Paul Erbel , Jayachandran Kizhakkedathu , Frédéric Villard
Nature Chemical Biology 15 ( 3) 304 -313
17
2019
Crystal structure of the anthrax lethal factor
Andrew D. Pannifer , Thiang Yian Wong , Robert Schwarzenbacher , Martin Renatus
Nature 414 ( 6860) 229 -233
365
2001