引用次数
引用: 460
H-指数: 11
I10-指数 : 14
出版物: 28
Passage variation of PC12 cells results in inconsistent susceptibility to externally induced apoptosis. ACS Chem Neurosci. 2017; 8 (1): 82–8
N Kinarivala , K Shah , TJ Abbruscato , PC Trippier
2
A CAR T Cell that Creates Cytotoxic Small Molecules to Overcome Cancer Resistance Mechanisms
T. Gardner , P.J. Lee , D. Wijewarnasuriya , D. Kinarivala
In Proceedings of the American Society of Gene and Cell Therapy Virtual Conference ( Online, Abstract 31)
2020
Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes.
Nihar Kinarivala , Lisa C. Standke , Tezcan Guney , Cheng Ji
Methods in Enzymology 638 69 -87
2020
Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis.
Nihar Kinarivala , Kaushik Shah , Thomas J. Abbruscato , Paul C. Trippier
ACS Chemical Neuroscience 8 ( 1) 82 -88
25
2017
Flupirtine derivatives as potential treatment for the neuronal ceroid lipofuscinoses.
Joelle Makoukji , Fadi Saadeh , Karl Albert Mansour , Sally El‐Sitt
Annals of clinical and translational neurology 5 ( 9) 1089 -1103
11
2018
Rational approaches, design strategies, structure activity relationship and mechanistic insights for therapeutic coumarin hybrids.
Harbinder Singh , Jatinder Vir Singh , Kavita Bhagat , Harmandeep Kaur Gulati
Bioorganic & Medicinal Chemistry 27 ( 16) 3477 -3510
71
2019
Exogenous Flupirtine as Potential Treatment for CLN3 Disease
Katia Maalouf , Joelle Makoukji , Sara Saab , Nadine J. Makhoul
Cells 9 ( 8) 1872
3
2020
Pharmacophore elucidation of phosphoiodyn A - Potent and selective peroxisome proliferator-activated receptor β/δ agonists with neuroprotective activity.
Nihar Kinarivala , Ji Ho Suh , Mina Botros , Paul Webb
Bioorganic & Medicinal Chemistry Letters 26 ( 8) 1889 -1893
8
2016
Synthesis and Antineoplastic Evaluation of Mitochondrial Complex II (Succinate Dehydrogenase) Inhibitors Derived from Atpenin A5.
Hezhen Wang , Bader Huwaimel , Kshitij Verma , James Miller
ChemMedChem 12 ( 13) 1033 -1044
20
2017
Discovery of Aromatic Carbamates that Confer Neuroprotective Activity by Enhancing Autophagy and Inducing the Anti-Apoptotic Protein B-Cell Lymphoma 2 (Bcl-2)
Nihar Kinarivala , Ronak Patel , Rose-Mary Boustany , Abraham Al-Ahmad
Journal of Medicinal Chemistry 60 ( 23) 9739 -9756
36
2017
An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening
Nihar Kinarivala , Ahmed Morsy , Ronak Patel , Angelica V. Carmona
ACS Pharmacology & Translational Science 3 ( 5) 931 -947
11
2020
Multi-Targeting Anticancer Agents: Rational Approaches, Synthetic Routes and Structure Activity Relationship
Harbinder Singh , Nihar Kinarivala , Sahil Sharma
Anti-cancer Agents in Medicinal Chemistry 19 ( 7) 842 -874
16
2019
Tailored Quinolines Demonstrate Flexibility to Exert Antitumor Effects through Varied Mechanisms-A Medicinal Perspective
Sachin Sharma , Arshdeep Singh , Sahil Sharma , Ram Sharma
Anti-cancer Agents in Medicinal Chemistry 21 ( 3) 288 -315
3
2021
Exploration of relative chemoselectivity in the hydrodechlorination of 2-chloropyridines
Nihar Kinarivala , Paul C. Trippier
Tetrahedron Letters 55 ( 39) 5386 -5389
8
2014
Rational approaches for the design of various GABA modulators and their clinical progression
Kavita Bhagat , Jatinder V Singh , Piyusha P Pagare , Nitish Kumar
Molecular Diversity 25 ( 1) 551 -601
9
2021
Engineering CAR-T cells to activate small-molecule drugs in situ
Thomas J Gardner , J Peter Lee , Christopher M Bourne , Dinali Wijewarnasuriya
Nature chemical biology 18 ( 2) 216 -225
16
2022
Targetable Micropharmacies: Cells that Produce Small-Molecule Drugs In Situ at the Tumor Site
Thomas J Gardner , Peter Lee , Dinali Wijewarnasuriya , Nihar Kinarivala
MOLECULAR THERAPY 28 ( 4) 190 -191
2020
Functional diversity of Gram-negative permeability barriers reflected in antibacterial activities and intracellular accumulation of antibiotics
Inga V Leus , Justyna Adamiak , Brinda Chandar , Vincent Bonifay
Antimicrobial Agents and Chemotherapy 67 ( 2) e01377 -22
9
2023
Small Molecules that Rescue Multiple Phenotypic Aberrations in an iPSC-Derived Neuron Model of CLN3 Disease
Nihar Kinarivala , Ahmed Morsy , Ronak Patel , Angelica Carmona
2020
Discovery of first-in-class peptidomimetic neurolysin activators possessing enhanced brain penetration and stability
Md Shafikur Rahman , Shikha Kumari , Shiva Hadi Esfahani , Saeideh Nozohouri
Journal of medicinal chemistry 64 ( 17) 12705 -12722
11
2021