Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis.

Nicolas Gengenbacher , Mahak Singhal , Carolin Mogler , Ling Hai
Cancer Discovery 11 ( 2) 424 -445

5
2021
Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

Marcos Rios Garcia , Brigitte Steinbauer , Kshitij Srivastava , Mahak Singhal
Cell Metabolism 26 ( 6) 842 -855.e5

66
2017
Preclinical validation of a novel metastasis-inhibiting Tie1 function-blocking antibody.

Mahak Singhal , Nicolas Gengenbacher , Silvia La Porta , Stephanie Gehrs
Embo Molecular Medicine 12 ( 6)

5
2020
Endothelial Tie1–mediated angiogenesis and vascular abnormalization promote tumor progression and metastasis

Silvia La Porta , Lise Roth , Mahak Singhal , Carolin Mogler
Journal of Clinical Investigation 128 ( 2) 834 -845

31
2018
Preclinical mouse solid tumour models: status quo, challenges and perspectives

Nicolas Gengenbacher , Mahak Singhal , Hellmut G. Augustin
Nature Reviews Cancer 17 ( 12) 751 -765

112
2017
Tumor Cell-Derived Angiopoietin-2 Promotes Metastasis in Melanoma.

Ashik Ahmed Abdul Pari , Mahak Singhal , Corinne Huebers , Carolin Mogler
Cancer Research 80 ( 12) 2586 -2598

4
2020
Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor

Arathy S. Kumar , Sankar Jagadeeshan , Anirudh Subramanian , Saravana Babu Chidambaram
Journal of Biological Chemistry 291 ( 23) 12310 -12321

3
2016
Endothelial cell fitness dictates the source of regenerating liver vasculature.

Mahak Singhal , Xiaoting Liu , Donato Inverso , Kai Jiang
Journal of Experimental Medicine 215 ( 10) 2497 -2508

15
2018
Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis

Mahak Singhal , Nicolas Gengenbacher , Ashik Ahmed Abdul Pari , Miki Kamiyama
Science Translational Medicine 13 ( 609) eabe6805

16
2021
Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice

Nathalie Tisch , Carolin Mogler , Ana Stojanovic , Robert Luck
EMBO Molecular Medicine 14 ( 6) e14121

2
2022
Activating NO--sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury

Hao He , Wu Yang , Nan Su , Chuankai Zhang
Journal of Experimental Medicine 220 ( 2) e20211422

2022
STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis

Ying Shen , Xiaohong Wang , Yi Liu , Mahak Singhal
Science Signaling 14 ( 712) eabj8393

21
2021
Sphingosine-1-phosphate recruits macrophages and microglia and induces a pro-tumorigenic phenotype that favors glioma progression

Lavinia Arseni , Rakesh Sharma , Norman Mack , Deepthi Nagalla
Cancers 15 ( 2) 479 -479

4
2023
Primary tumor–derived systemic nANGPTL4 inhibits metastasis

Corinne Hübers , Ashik Ahmed Abdul Pari , Denise Grieshober , Martin Petkov
Journal of Experimental Medicine 220 ( 1) e20202595 -e20202595

17
2022
Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization

Matthia A Karreman , Alexander T Bauer , Gergely Solecki , Anna S Berghoff
Cancer research 83 ( 8) 1299 -1314

16
2023
KANK4 Promotes Arteriogenesis by Potentiating VEGFR2 Signaling in a TALIN-1–Dependent Manner

Chonghe Zhang , Hao He , Jianing Dai , Yunxia Li
Arteriosclerosis, Thrombosis, and Vascular Biology 42 ( 6) 772 -788

2
2022
Vascular Smooth Muscle Cell-expressed Tie2 Controls Atherosclerosis Progression

Stephanie S Kapel , Jingjing Shi , Zulfiyya Hasanov , Sila Appak-Baskoy
Arteriosclerosis, Thrombosis, and Vascular Biology 38 ( Suppl_1) A450 -A450

2018
LRG1 Destabilizes Tumor Vessels and Restricts Immunotherapeutic Potency

Marie N O’Connor , David M Kallenberg , Carlotta Camilli , Camilla Pilotti
Social Science Research Network

8
2020
Emerging paradigms in metastasis research

Ashik Ahmed Abdul Pari , Mahak Singhal , Hellmut G Augustin
Journal of Experimental Medicine 218 ( 1) e20190218 -e20190218

24
2020