Jamie Fletcher
机构: Principal Scientist, Children's Cancer Institute
每年引用次数
引用次数
引用: 11,198
H-指数: 33
I10-指数 : 50
出版物: 78
Subversion of the Bcl-2 life/death switch in cancer development and therapy
J.M. ADAMS , D.C.S. HUANG , A. STRASSER , S. WILLIS
Cold Spring Harbor Symposia on Quantitative Biology 70 ( 1) 469 -477
28
2005
RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model
F L Byrne , L Yang , P A Phillips , L M Hansford
Oncogene 33 ( 7) 882 -890
47
2014
BH3-only proteins: orchestrating cell death
J I Fletcher , D C S Huang
Cell Death & Differentiation 13 ( 8) 1268 -1271
20
2006
Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma.
Natalia Issaeva , Anahid Ehteda , Katerina V Gurova , Mawar Karsa
Clinical Cancer Research
2021
The Structure of Ap4A Hydrolase Complexed with ATP-MgFx Reveals the Basis of Substrate Binding
Jamie I Fletcher , James D Swarbrick , Danuta Maksel , Kenwyn R Gayler
Structure 10 ( 2) 205 -213
28
2002
The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel
Jamie I Fletcher , Bogdan E Chapman , Joel P Mackay , Merlin EH Howden
Structure 5 ( 11) 1525 -1535
103
1997
Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition
Kimberley M Hanssen , Michelle Haber , Jamie I Fletcher
Drug Resistance Updates 59 100795
15
2021
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma
Jordan F Hastings , Sharissa L Latham , Alvin Kamili , Madeleine S Wheatley
Science Advances 9 ( 9) eabp8314
2023
Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma
Vinod Vijay Subhash , Libby Huang , Alvin Kamili , Marie Wong
British journal of cancer 126 ( 3) 482 -491
4
2022
The structure of a novel insecticidal neurotoxin, ω-atracotoxin-HV1, from the venom of an Australian funnel web spider
Jamie I Fletcher , Ross Smith , Séan I O'Donoghue , Michael Nilges
Nature Structural Biology 4 559 -566
228
1997
Functional significance of the β-hairpin in the insecticidal neurotoxin ω-atracotoxin-Hv1a
Hugo W Tedford , Jamie I Fletcher , Glenn F King
Journal of Biological Chemistry 276 26568 -26576
82
2001
High‐resolution solution structure of gurmarin, a sweet‐taste‐suppressing plant polypeptide
Jamie I Fletcher , Andrew J Dingley , Ross Smith , Mark Connor
European Journal of Biochemistry 264 525 -533
49
1999
Addition of AMXT1501 (polyamine uptake inhibitor) plus DFMO (polyamine synthesis inhibitor) to standard-of-care chemotherapy/anti-GD2 antibody in the TH-MYCN mouse neuroblastoma model, enhances efficacy compared to addition of DFMO alone
Jayne Murray , Ruby Pandher , Lin Xiao , Klaartje Somers
MOLECULAR CANCER THERAPEUTICS 22 ( 12)
2023
In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer
Loretta MS Lau , Chelsea Mayoh , Jinhan Xie , Paulette Barahona
EMBO molecular medicine 14 ( 4) e14608 -e14608
19
2022
Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities
Claire Xin Sun , Paul Daniel , Gabrielle Bradshaw , Hui Shi
Cancer cell 41 ( 4) 660 -677. e7
17
2023
SYST-15 GENERATION AND MULTI-DIMENSIONAL PROFILING OF A CHILDHOOD CANCER CELL LINE ATLAS DEFINES NEW THERAPEUTIC OPPORTUNITIES
Paul Daniel , Claire Xin Sun , Gabrielle Bradshaw , Hui Shi
Neuro-Oncology Advances 5 ( Supplement_3) iii30 -iii30
2023
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation
Christopher B Nelson , Samuel Rogers , Kaushik Roychoudhury , Yaw Sing Tan
Nature Communications 15 ( 1) 1385 -1385
1
2024
“We Have All This Knowledge to Give, So Use Us as a Resource”: Partnering with Adolescent and Young Adult Cancer Survivors to Determine Consumer-Led Research Priorities
Clarissa E Schilstra , Ursula M Sansom-Daly , Maria Schaffer , Joanna E Fardell
Journal of Adolescent and Young Adult Oncology 11 ( 2) 211 -222
9
2022
A Myc activity signature predicts poor clinical outcomes in Myc-associated cancers
Jung MoonSun , Amanda J. Russell , Liu Bing , Joshy George
Cancer Research
104
2016
Proapoptotic Bak Is Sequestered by Mcl-1 and Bcl-xL, but Not Bcl-2, Until Displaced by BH3-only Proteins
Simon N Willis , Lin Chen , Grant Dewson , Andrew Wei
Genes & Development 19 ( 11) 1294 -1305
1,093
2005