In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia

M. C. Skala , K. M. Riching , A. Gendron-Fitzpatrick , J. Eickhoff
Proceedings of the National Academy of Sciences of the United States of America 104 ( 49) 19494 -19499

675
2007
Discovery and resistance mechanism of a selective CDK12 degrader.

Matthew J Berberich , Nathanael S Gray , Danette L Daniels , Tinghu Zhang
Nature Chemical Biology 17 ( 6) 675 -683

47
2021
Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression.

Scott Gehler , Suzanne M. Ponik , Kristin M Riching , Patricia J. Keely
Critical Reviews in Eukaryotic Gene Expression 23 ( 2) 139 -157

62
2013
R-Ras regulates β1-integrin trafficking via effects on membrane ruffling and endocytosis

Matthew W Conklin , Aude Ada-Nguema , Maddy Parsons , Kristin M Riching
BMC Cell Biology 11 ( 1) 14 -14

29
2010
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Satomi Imaide , Kristin M Riching , Nikolai Makukhin , Vesna Vetma
Nature chemical biology 17 ( 11) 1157 -1167

57
2021
Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs

Nan Bai , Kristin M Riching , Aman Makaju , Hao Wu
Journal of Biological Chemistry 298 ( 4)

38
2022
In vivo multiphoton fluorescence lifetime imaging<? xpp qa?> of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia

Melissa C Skala , Kristin M Riching , Damian K Bird , Annette Gendron-Fitzpatrick
Journal of biomedical optics 12 ( 2) 024014 -024014

407
2007
In vivo multiphoton fluorescence lifetime imaging of protein-bound and free NADH in normal and pre-cancerous epithelia

Melissa C Skala , Kristin M Riching , Damian K Bird , Annette Gendron-Fitzpatrick
Journal of biomedical optics 12 ( 2) 024014 -024014

49
2007
In vivo Multiphoton Fluorescence Lifetime Imaging of Free and Protein-bound NADH in Normal and Pre-cancerous Epithelia

Melissa C Skala , Nirmala Ramanujam , Kristin M Riching , Kristin M Vrotsos
Biomedical Topical Meeting SG3 -SG3

2006
The Effect of ECM Stiffness and Topography on Breast Cancer Cell Migration

Kristin M Riching , Kevin W Eliceiri , Patricia J Keely

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Gisele Nishiguchi , Lauren G Mascibroda , Sarah M Young , Elizabeth A Caine
Nature Communications 15 ( 1) 482 -482

4
2024
Translating PROTAC chemical series optimization into functional outcomes underlying BRD7 and BRD9 protein degradation

Kristin M Riching , James D Vasta , Scott J Hughes , Vittoria Zoppi
Current Research in Chemical Biology 1 100009 -100009

15
2021
SRSF2 plays an unexpected role as reader of m5C on mRNA, linking epitranscriptomics to cancer

Hai-Li Ma , Martin Bizet , Christelle Soares Da Costa , Frédéric Murisier
Molecular cell 83 ( 23) 4239 -4254. e10

6
2023
3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

Kristin M Riching , Benjamin L Cox , Max R Salick , Carolyn Pehlke
Biophysical Journal 107 ( 11) 2546 -2558

395
2014
ScholarWorks@ Georgia State Universit y

Kristin M Riching , Benjamin L Cox , Max R Salick , Carolyn Pehleke

The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation

Kristin M Riching , Elizabeth A Caine , Marjeta Urh , Danette L Daniels
Chemical Society Reviews 51 ( 14) 6210 -6221

20
2022
Kinetic detection of E3: PROTAC: target ternary complexes using NanoBRET technology in live cells

Sarah D Mahan , Kristin M Riching , Marjeta Urh , Danette L Daniels
Targeted Protein Degradation: Methods and Protocols 151 -171

9
2021
Monitoring PROTAC interactions in biochemical assays using Lumit immunoassays

Ellen K Crummy , Elizabeth A Caine , Dareen Mikheil , Cesear Corona
Academic Press 681 81 -113

2023
Real-time monitoring of PROTAC and molecular glue targeted degradation in living cells

Neal C Cosby , Kristin M Riching , Sarah Mahan , Elizabeth A Caine
Cancer Research 80 ( 16_Supplement) 5230 -5230

2020
The Sobering Effect of Matrix Alignment on Breast Cancer Cell Migration

Kristin M Riching
The University of Wisconsin-Madison

2013