Indazole compounds and their uses

Nathanael Gray , Xianming Deng , Wenjun Zhou

1
2011
SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND ABL AND METHODS OF USE

Nathanael S. Gray , Amy Wojciechowski , Xianming Deng , Barun Okram

2017
Abstract P70: SPAK/OSR1 Signaling as a Novel Target for Post-Stroke Oxidative Stress Brain Injury

Kristopher T Kahle , Gulnaz Begum , Xianming Deng , Dandan Sun
Stroke 52

2021
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor.

Yun Chen , Hongbin He , Bolong Lin , Yun Chen
Cellular & Molecular Immunology 18 ( 6) 1425 -1436

28
2021
The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma

Elisabetta Rovida , Giovanni Di Maira , Ignazia Tusa , Stefania Cannito
Gut 64 ( 9) 1454 -1465

31
2015
Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein.

Qingkai Yang , Xianming Deng , Bingwen Lu , Michael Cameron
Cancer Cell 18 ( 3) 258 -267

211
2010
ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal translocation of TSC2 after DNA damage

Mingdong Liu , Taoling Zeng , Xin Zhang , Chunyan Liu
Nature Communications 9 ( 1) 4139

34
2018
6
2015
Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine.

Wei Li , Yunzhan Li , Zehua Liu , Nattha Kerdsakundee
Biomaterials 185 322 -332

30
2018
Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors

Yun Chen , Hongbin He , Hua Jiang , Li Li
Bioorganic & Medicinal Chemistry Letters 30 ( 7) 127021

5
2020
A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases

Maoyuan Tian , Taoling Zeng , Mingdong Liu , Shang Han
Journal of Biological Chemistry 294 ( 8) 2880 -2891

24
2019
Kribbella mirabilis sp. nov., isolated from rhizosphere soil of a herbaceous plant, Mirabilis jalapa L.

Dan Li , Jiaojiao Song , Yaojian Huang , Siyang Song
International Journal of Systematic and Evolutionary Microbiology 65 ( 9) 3143 -3147

4
2015
Nonomuraea ceibae sp. nov., an actinobacterium isolated from Ceiba speciosa rhizosphere.

Fei Wang , Jindi Shi , Yaojian Huang , Yingying Wu
International Journal of Systematic and Evolutionary Microbiology 67 ( 5) 1158 -1162

6
2017
Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones.

Xianming Deng , Jonathan M. Elkins , Jinwei Zhang , Qingkai Yang
European Journal of Medicinal Chemistry 70 758 -767

50
2013
Expanding the diversity of allosteric bcr-abl inhibitors.

Xianming Deng , Barun Okram , Qiang Ding , Jianming Zhang
Journal of Medicinal Chemistry 53 ( 19) 6934 -6946

53
2010
Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors

Nathanael S. Gray , Fleur M. Ferguson , Jing Ni , Tinghu Zhang
ACS Medicinal Chemistry Letters 7 ( 10) 908 -912

18
2016
Environmentally responsive dual-targeting nanotheranostics for overcoming cancer multidrug resistance

Caixia Yang , Xin Pang , Weihai Chen , Xiaoyong Wang
Chinese Science Bulletin 64 ( 10) 705 -714

14
2019
Broad spectrum alkynyl inhibitors of T315I Bcr-Abl

Xianming Deng , Sang Min Lim , Jianming Zhang , Nathanael S. Gray
Bioorganic & Medicinal Chemistry Letters 20 ( 14) 4196 -4200

35
2010
Discovery of novel 1H-imidazol-2-yl-pyrimidine-4,6-diamines as potential antimalarials

Xianming Deng , Advait Nagle , Tao Wu , Tomoyo Sakata
Bioorganic & Medicinal Chemistry Letters 20 ( 14) 4027 -4031

23
2010