Robert Fledrich
机构: Professor of Neuroanatomy, Institute of Anatomy, Leipzig University
主页: fledrich-lab.de
每年引用次数
引用次数
引用: 1,640
H-指数: 19
I10-指数 : 21
出版物: 62
2014
Hyperactivity is a Core Endophenotype of Elevated Neuregulin-1 Signaling in Embryonic Glutamatergic Networks.
Robert Fledrich , Katrin Willig , Katrin Willig , Christian Dullin
Schizophrenia Bulletin
2021
AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A.
Benoit Gautier , Helene Hajjar , Sylvia Soares , Jade Berthelot
Nature Communications 12 ( 1) 2356 -2356
1
2021
Axo-glial interdependence in peripheral nerve development
Robert Fledrich , Theresa Kungl , Klaus-Armin Nave , Ruth M. Stassart
Development 146 ( 21) dev151704
11
2019
The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration.
Gerd Meyer zu Horste , Timo A. Miesbach , Johanna I. Muller , Robert Fledrich
Neurobiology of Disease 42 ( 1) 1 -8
44
2011
Aktuelles zur Charcot-Marie-Tooth-Erkrankung
Ruth M. Stassart , Robert Fledrich , Michael W. Sereda , Michael Bartl
Nervenheilkunde 38 ( 06) 389 -396
2019
A role for Schwann cell-derived neuregulin-1 in remyelination
Ruth M Stassart , Robert Fledrich , Viktorija Velanac , Bastian G Brinkmann
Nature Neuroscience 16 ( 1) 48 -54
180
2013
Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A
Robert Fledrich , Ruth M Stassart , Axel Klink , Lennart M Rasch
Nature Medicine 20 ( 9) 1055 -1061
117
2014
A rat model of Charcot–Marie–Tooth disease 1A recapitulates disease variability and supplies biomarkers of axonal loss in patients
Robert Fledrich , Beate Schlotter-Weigel , Tuuli J. Schnizer , Sven P. Wichert
Brain 135 ( 1) 72 -87
39
2012
Myelinating Glia-Specific Deletion of Fbxo7 in Mice Triggers Axonal Degeneration in the Central Nervous System Together with Peripheral Neuropathy.
Sabitha Joseph , Siv Vingill , Olaf Jahn , Robert Fledrich
The Journal of Neuroscience 39 ( 28) 5606 -5626
3
2019
Biomarkers predict outcome in Charcot-Marie-Tooth disease 1A
Robert Fledrich , Manoj Mannil , Andreas Leha , Caroline Ehbrecht
Journal of Neurology, Neurosurgery, and Psychiatry 88 ( 11) 941 -952
15
2017
Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity
Jolien Wolbert , Xiaolin Li , Michael Heming , Anne K. Mausberg
Proceedings of the National Academy of Sciences of the United States of America 117 ( 17) 9466 -9476
67
2020
NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.
Robert Fledrich , Dagmar Akkermann , Vlad Schütza , Tamer A. Abdelaal
Nature Communications 10 ( 1) 1467
19
2019
Long term AAV2/9-mediated silencing of PMP22 prevents CMT1A disease in rats and validates skin biomarkers as treatment outcome measure
Benoit Gautier , Helene Hajjar , Sylvia Soares , Jade Berthelot
bioRxiv
1
2020
Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking
Julia Patzig , Kathrin Kusch , Robert Fledrich , Maria A. Eichel
Glia 64 ( 1) 155 -174
19
2016
Proteome profile of peripheral myelin in healthy mice and in a neuropathy model
Sophie B Siems , Olaf Jahn , Maria A Eichel , Nirmal Kannaiyan
eLife 9
15
2020
Progesterone Antagonist Therapy in a Pelizaeus-Merzbacher Mouse Model
Thomas Prukop , Dirk B. Epplen , Tobias Nientiedt , Sven P. Wichert
American Journal of Human Genetics 94 ( 4) 533 -546
18
2014
CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves.
Maria A. Eichel , Vasiliki-Ilya Gargareta , Elisa D’Este , Robert Fledrich
Nature Communications 11 ( 1) 4514 -4514
3
2020
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease
Erik Schäffner , Mar Bosch-Queralt , Julia M Edgar , Maria Lehning
Nature Neuroscience 1 -11
1
2023
Schwann cell functions in peripheral nerve development and repair
Mar Bosch-Queralt , Robert Fledrich , Ruth M Stassart
Neurobiology of Disease 176 105952
2
2023