Georg Lentzen
机构: Managing Director, b-value AG
每年引用次数
引用次数
引用: 2,891
H-指数: 23
I10-指数 : 26
出版物: 57
Targeting the A site RNA of the Escherichia coli ribosomal 30 S subunit by 2'-O-methyl oligoribonucleotides: a quantitative equilibrium dialysis binding assay and differential effects of aminoglycoside antibiotics.
Arthur ABELIAN , Andrew P. WALSH , Georg LENTZEN , Fareed ABOUL-ELA
Biochemical Journal 383 ( 2) 201 -208
13
2004
Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY.
JUNUTULA R. JAGATH , NATALIA B. MATASSOVA , ERIK DE LEEUW , JENS M. WARNECKE
RNA 7 ( 2) 293 -301
62
2001
NATALIA MATASSOVA², ALASTAIR IH MURCHIE², FAREED ABOUL-ELA³ and MOHAMMAD AFSHAR'Departments of Chemistry, Drug Discovery, Structural Biology and* Drug Design, RiboTargets Ltd., Granta Park, Abington, Cambridge
MARTIN J DRYSDALE , GEORG LENTZEN
Progress in Medicinal Chemistry 73 -73
2002
Forms of E. Coli Tryptophan Synthase A Phosphorus-31 NMR Study
P BARTHOLMES , G LENTZEN , B RECKMANN
Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors: Proceedings of the 8th International Symposium on Vitamin B6 and Carbonyl Catalysis, Held in Osaka, Japan, October 15-19, 1990 199 269 -269
2013
EFFECT OF ESCHERICHIA-COLI 4.5 S RNA ON ELONGATION FACTOR-G AND RIBOSOME DEPENDENT GTP HYDROLYSIS
G LENTZEN , W WINTERMEYER
BIOLOGICAL CHEMISTRY HOPPE-SEYLER 372 ( 9) 705 -706
1991
Structure of 4.5S RNA in the signal recognition particle of Escherichia coli as studied by enzymatic and chemical probing.
Bernard Ehresmann , Wolfgang Wintermeyer , Georg Lentzen , Chantal Ehresmann
RNA 2 ( 3) 244 -253
41
1996
Extremolytes give us a hint for designing synthetic compounds as potential inhibitors of amyloid formation
Georg Lentzen , Jungki Ryu , Chan Beum Park
한국생물공학회 추계학술발표대회 218 -218
2007
Kompatible solute enthaltende mittel zur oralen verwendung
Georg Lentzen , Jean Krutmann , Thomas Schwarz
2006
The effect of compatible solute ectoines on the structural organization of lipid monolayer and bilayer membranes
Rakesh Kumar Harishchandra , Stephanie Wulff , Georg Lentzen , Thorsten Neuhaus
Biophysical Chemistry 150 ( 1-3) 37 -46
85
2010
The functioning of the SRP receptor FtsY in protein-targeting in E. coli is correlated with its ability to bind and hydrolyse GTP.
Ron Kusters , Georg Lentzen , Elaine Eppens , Anton van Geel
FEBS Letters 372 ( 2) 253 -258
45
1995
Formation of SRP‐like particle induces a conformational change in E. coli 4.5S RNA
Georg Lentzen , Bernhard Dobberstein , Wolfgang Wintermeyer
FEBS Letters 348 ( 3) 233 -238
26
1994
Structure-based design of agents targeting the bacterial ribosome.
Justin Bower , Martin Drysdale , Richard Hebdon , Allan Jordan
Bioorganic & Medicinal Chemistry Letters 13 ( 15) 2455 -2458
23
2003
Extremolytes: Natural compounds from extremophiles for versatile applications.
Georg Lentzen , Thomas Schwarz
Applied Microbiology and Biotechnology 72 ( 4) 623 -634
242
2006
Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's β‐amyloid
Mathumai Kanapathipillai , Georg Lentzen , Michael Sierks , Chan Beum Park
FEBS Letters 579 ( 21) 4775 -4780
100
2005
Structural Basis for Contrasting Activities of Ribosome Binding Thiazole Antibiotics
Georg Lentzen , Roscoe Klinck , Natalia Matassova , Fareed Aboul-ela
Chemistry & Biology 10 ( 8) 769 -778
122
2003
Interactions of Designer Antibiotics and the Bacterial Ribosomal Aminoacyl-tRNA Site
James B. Murray , Samy O. Meroueh , Rupert J.M. Russell , Georg Lentzen
Chemistry & Biology 13 ( 2) 129 -138
35
2006
Novel effects of ectoine, a bacteria-derived natural tetrahydropyrimidine, in experimental colitis
Heba Abdel-Aziz , Walaa Wadie , Dalaal M. Abdallah , Georg Lentzen
Phytomedicine 20 ( 7) 585 -591
35
2013
RNA as a drug target.
Martin J. Drysdale , Georg Lentzen , Natalia Matassova , Alastair I.H. Murchie
Progress in Medicinal Chemistry 39 73 -119
17
2002
INTERACTION OF GUANINE NUCLEOTIDES WITH THE SIGNAL RECOGNITION PARTICLE FROM ESCHERICHIA COLI
Junutula R. Jagath , Marina V. Rodnina , Georg Lentzen , Wolfgang Wintermeyer
Biochemistry 37 ( 44) 15408 -15413
55
1998
Inhibition of β-amyloid peptide aggregation and neurotoxicity by α-d-mannosylglycerate, a natural extremolyte
Jungki Ryu , Mathumai Kanapathipillai , Georg Lentzen , Chan Beum Park
Peptides 29 ( 4) 578 -584
35
2008