The mitochondrial carnitine carrier protein: cDNA cloning, primary structure and comparison with other mitochondrial transport proteins.
Cesare INDIVERI , Vito IACOBAZZI , Nicola GIANGREGORIO , Ferdinando PALMIERI
Biochemical Journal 321 ( 3) 713 -719
139
1997
A Prospective Repurposing of Dantrolene as a Multitarget Agent for Alzheimer's Disease
Bolognino , Giangregorio , Pisani , de Candia
Molecules 24 ( 23) 4298
6
2019
The hyperchromatic supranuclear stria corresponds to the Golgi apparatus in nasal ciliated cells.
Nicola Giangregorio , Giorgio Ciprandi , Matteo Gelardi , Maria Favia
Acta bio-medica : Atenei Parmensis 91 ( 2) 373 -375
2
2020
The Mitochondrial Carnitine Acyl-carnitine Carrier (SLC25A20): Molecular Mechanisms of Transport, Role in Redox Sensing and Interaction with Drugs.
Nicola Giangregorio , Cesare Indiveri , Cesare Indiveri , Lara Console
Biomolecules 11 ( 4) 521
2021
Synthesis and biological evaluation of dantrolene-like hydrazide and hydrazone analogues as multitarget agents for neurodegenerative diseases.
Nicola Giangregorio , Saverio Cellamare , Cosimo D Altomare , Marco Catto
ChemMedChem
2021
Functional characterization of residues within the carnitine/acylcarnitine translocase RX2PANAAXF distinct motif.
J. Ramon De Lucas , Cesare Indiveri , Annamaria Tonazzi , Patricia Perez
Molecular Membrane Biology 25 ( 2) 152 -163
23
2008
Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl)hydrazone: A water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity.
Leonardo Pisani , Annalisa De Palma , Nicola Giangregorio , Daniela V. Miniero
European Journal of Pharmaceutical Sciences 109 381 -388
19
2017
Post-translational modification by acetylation regulates the mitochondrial carnitine/acylcarnitine transport protein
Nicola Giangregorio , Annamaria Tonazzi , Lara Console , Cesare Indiveri
Molecular and Cellular Biochemistry 426 ( 1) 65 -73
12
2017
Site-Directed Mutagenesis and Chemical Modification of the Six Native Cysteine Residues of the Rat Mitochondrial Carnitine Carrier: Implications for the Role of Cysteine-136 †
Cesare Indiveri , Nicola Giangregorio , Vito Iacobazzi , Ferdinando Palmieri
Biochemistry 41 ( 27) 8649 -8656
40
2002
Carnitine Traffic in Cells. Link With Cancer.
Lara Console , Mariafrancesca Scalise , Tiziano Mazza , Lorena Pochini
Frontiers in Cell and Developmental Biology 8 583850
5
2020
Mitochondrial carnitine/acylcarnitine transporter, a novel target of mercury toxicity.
Annamaria Tonazzi , Nicola Giangregorio , Lara Console , Mariafrancesca Scalise
Chemical Research in Toxicology 28 ( 5) 1015 -1022
16
2015
Mitochondrial carnitine/acylcarnitine translocase: insights in structure/ function relationships. Basis for drug therapy and side effects prediction.
Annamaria Tonazzi , Nicola Giangregorio , Lara Console , Cesare Indiveri
Mini-reviews in Medicinal Chemistry 15 ( 5) 396 -405
20
2015
Identification by Site-directed Mutagenesis and Chemical Modification of Three Vicinal Cysteine Residues in Rat Mitochondrial Carnitine/Acylcarnitine Transporter
Annamaria Tonazzi , Nicola Giangregorio , Cesare Indiveri , Ferdinando Palmieri
Journal of Biological Chemistry 280 ( 20) 19607 -19612
41
2005
Carnitine/acylcarnitine translocase and carnitine palmitoyltransferase 2 form a complex in the inner mitochondrial membrane
Lara Console , Nicola Giangregorio , Cesare Indiveri , Annamaria Tonazzi
Molecular and Cellular Biochemistry 394 ( 1) 307 -314
13
2014
Relationships of Cysteine and Lysine residues with the substrate binding site of the mitochondrial ornithine/citrulline carrier: An inhibition kinetic approach combined with the analysis of the homology structural model
Annamaria Tonazzi , Nicola Giangregorio , Ferdinando Palmieri , Cesare Indiveri
Biochimica et Biophysica Acta (BBA) - Biomembranes 1718 ( 1-2) 53 -60
25
2005
Exploiting Cysteine Residues of SLC Membrane Transporters as Targets for Drugs.
Mariafrancesca Scalise , Lara Console , Michele Galluccio , Lorena Pochini
SLAS DISCOVERY: Advancing the Science of Drug Discovery 24 ( 9) 867 -881
2
2019
Structure/function relationships of the human mitochondrial ornithine/citrulline carrier by Cys site-directed mutagenesis. Relevance to mercury toxicity
Nicola Giangregorio , Annamaria Tonazzi , Lara Console , Michele Galluccio
International Journal of Biological Macromolecules 120 93 -99
3
2018
The mitochondrial carnitine/acylcarnitine carrier: Function, structure and physiopathology
Cesare Indiveri , Vito Iacobazzi , Annamaria Tonazzi , Nicola Giangregorio
Molecular Aspects of Medicine 32 ( 4) 223 -233
134
2011
Glutathione controls the redox state of the mitochondrial carnitine/acylcarnitine carrier Cys residues by glutathionylation.
Nicola Giangregorio , Ferdinando Palmieri , Cesare Indiveri
Biochimica et Biophysica Acta 1830 ( 11) 5299 -5304
28
2013
Characterization of Exosomal SLC22A5 (OCTN2) carnitine transporter
Lara Console , Mariafrancesca Scalise , Annamaria Tonazzi , Nicola Giangregorio
Scientific Reports 8 ( 1) 3758
13
2018