Adenosine A3 agonists reverse neuropathic pain via T cell–mediated production of IL-10
Daniela Salvemini , Daniel Hawiger , Carla Ghelardini , Adeleye Opejin
Journal of Clinical Investigation 131 ( 7)
2021
Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts.
Tina C Wan , Dilip K Tosh , Lili Du , Elizabeth T Gizewski
BMC Pharmacology 11 ( 1) 11 -11
20
2011
A3 adenosine receptor agonists containing dopamine moieties for enhanced interspecies affinity
Dilip K Tosh , Veronica Salmaso , Ryan G Campbell , Harsha Rao
European journal of medicinal chemistry 228 113983 -113983
8
2022
2-Substituted (N)-Methanocarba A3 Adenosine Receptor Agonists: In silico, in vitro and in vivo Characterization
Kenneth Jacobson , Dilip K Tosh , Chunxia Cronin , Matteo Pavan
Journal of Pharmacology and Experimental Therapeutics 389 ( S3)
2024
Optical control of adenosine A3 receptor function in psoriasis
Marc López-Cano , Ingrid Filgaira , Ernest G Nolen , Gisela Cabré
Pharmacological research 170 105731 -105731
9
2021
Targeting the A3 adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice
Anand Kumar Singh , Rajasekaran Mahalingam , Silvia Squillace , Kenneth A Jacobson
Acta Neuropathologica Communications 10 ( 1) 11 -11
25
2022
Methanocarba adenosine derivatives, pharmaceutical compositions, and method of reducing intraocular pressure
Kenneth A Jacobson , Dilip K Tosh
18
2013
A3 adenosine receptor agonists and antagonists
Kenneth A Jacobson , Dilip K Tosh
14
2014
Adenosine receptor agonists, partial agonists, and antagonists
Kenneth A Jacobson , Dilip K Tosh
13
2015
Expanding the repertoire of methanocarba nucleosides from purinergic signaling to diverse targets
Kenneth A Jacobson , Veronica Salmaso , R Rama Suresh , Dilip K Tosh
RSC Medicinal Chemistry 12 ( 11) 1808 -1825
10
2021
A3 adenosine receptor agonists
Kenneth A Jacobson , Dilip K Tosh , Daniela Salvemini
6
2018
Adenosine A3 receptor (A3AR) agonist for the treatment of bleomycin-induced lung fibrosis in mice
Silvia Sgambellone , Silvia Marri , Stefano Catarinicchia , Alessandro Pini
International Journal of Molecular Sciences 23 ( 21) 13300 -13300
5
2022
Effects of purinergic receptor deletion or pharmacologic modulation on pulmonary inflammation in mice
Gregory S Whitehead , Tadeusz P Karcz , Dilip K Tosh , Young-Hwan Jung
ACS Pharmacology & Translational Science 5 ( 10) 973 -984
4
2022
Interaction of A3 adenosine receptor ligands with the human multidrug transporter ABCG2
Biebele Abel , Megumi Murakami , Dilip K Tosh , Jinha Yu
European journal of medicinal chemistry 231 114103 -114103
3
2022
Discovery of next generation A (3) adenosine receptor selective agonists for treatment of chronic neuropathic pain
Dilip K Tosh , Silvia Paoletta , Amanda Ford , Kali Janes
Abstracts of Papers of the American Chemical Society 247
2
2014
Structure activity relationships of 5-HT2B and 5-HT2C serotonin receptor antagonists: N6, C2 and 5′-Modified (N)-methanocarba-adenosine derivatives
Dilip K Tosh , Maggie M Calkins , Marko S Ivancich , Hailey A Bock
European Journal of Medicinal Chemistry 259 115691 -115691
1
2023
First Potent Macrocyclic A3 Adenosine Receptor Agonists Reveal G-Protein and β-Arrestin2 Signaling Preferences
Dilip K Tosh , Courtney L Fisher , Veronica Salmaso , Tina C Wan
ACS Pharmacology & Translational Science 6 ( 9) 1288 -1305
1
2023
Selective P2Y6 receptor agonists: Extended phosphate and (S)-methanocarba ribonucleotide analogs
Hiroshi Maruoka , Hyojin Ko , Dilip K Tosh , Artem Melman
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238
1
2009
Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A3 adenosine receptor in HL-60 cells
Zhan-Guo Gao , Weiping Chen , Ray R Gao , Jonathan Li
Purinergic Signalling 1 -12
2024
2-Amino-5-arylethynyl-thiophen-3-yl-(phenyl) methanones as A1 Adenosine Receptor Positive Allosteric Modulators
Paola Oliva , R Rama Suresh , Silvia Pasquini , Veronica Salmaso
ACS Medicinal Chemistry Letters 14 ( 12) 1640 -1646
2023