Structures and variable functions of TRP channels

Yoshitsugu Uriu , Daisuke Kozai , Tomohiro Numata , Nobuaki Takahashi
Seikagaku 81 ( 11) 962

3
2009
Mechanosensor TRPM7 channel and its physiological role in cell volume regulation

Tomohiro Numata
Proceedings of Annual Meeting of the Physiological Society of Japan Proceedings of Annual Meeting of the Physiological Society of Japan 009 -009

2008
Volume-sensitive, outwardly rectifying chloride channel activity in cisplatin-induced apoptosis of epidermoid cancer cells

Tomoko Ise , Takahiro Shimizu , Hana Inoue , Tomohiro Numata
Proceedings of Annual Meeting of the Physiological Society of Japan Proceedings of Annual Meeting of the Physiological Society of Japan 020 -020

2007
Roles of volume-sensitive Cl− channels in cell volume regulation and AVP secretion in vasopressin neurons

Yoichi Ueta , Tomohiro Numata , Kaori Sato , Yasunobu Okada
Proceedings of Annual Meeting of the Physiological Society of Japan Proceedings of Annual Meeting of the Physiological Society of Japan 081 -081

2008
TRPM7 channels are activated by cell swelling and involved in the cell volume regulation

Takahiro Shimizu , Tomohiro Numata , Yasunobu Okada
Proceedings of Annual Meeting of the Physiological Society of Japan Proceedings of Annual Meeting of the Physiological Society of Japan

2005
The role of reactive oxygen species in anion channel activation induced by a mitochondrion-mediated apoptosis inducer

Takahiro Shimizu , Tomohiro Numata , Yasunobu Okada
Proceedings of Annual Meeting of the Physiological Society of Japan Proceedings of Annual Meeting of the Physiological Society of Japan

2004
Vasopressin Neurons Respond to Hyperosmotic Stimulation with Regulatory Volume Increase and Secretory Volume Decrease by Activating Ion Transporters and Ca 2+ Channels

Yoichi Ueta , Kaori Sato-Numata , Kaori Sato-Numata , Tomohiro Numata
Cellular Physiology and Biochemistry 55 119 -134

2021
BK Channels Are Activated by Functional Coupling With L-Type Ca2+ Channels in Cricket Myocytes

Masami Yoshino , Tomohiro Numata , Tomohiro Numata , Kaori Sato-Numata
Frontiers in Insect Science 1

2021
A pathogenic C-terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7

Shigeki Kiyonaka , Tomohiro Numata , Yasuo Mori , Yoshikatsu Kanai
Journal of Physiological Sciences 60

2010
TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel.

Kaori Sato-Numata , Kaori Sato-Numata , Meredith C Hermosura , Tomohiro Numata
Communications Biology 4 ( 1) 599 -599

2021
Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing

Tomohiro Numata , Kunichika Tsumoto , Kazunori Yamada , Tatsuki Kurokawa
Scientific Reports 7 ( 1) 9760

3
2017
Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation

Ryoki Nakamura , Tomohiro Numata , Go Kasuya , Takeshi Yokoyama
Communications Biology 3 ( 1) 240

7
2020
Proton Conductivity through the Human TRPM7 Channel and Its Molecular Determinants

Tomohiro Numata , Yasunobu Okada
Journal of Biological Chemistry 283 ( 22) 15097 -15103

25
2008
Roles of volume-regulatory anion channels, VSOR and Maxi-Cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction.

Yasunobu Okada , Tomohiro Numata , Kaori Sato-Numata , Ravshan Z. Sabirov
Current Topics in Membranes 83 205 -283

35
2019
TRPM7 is involved in acid-induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells

Tomohiro Numata , Kaori Sato‐Numata , Yasunobu Okada
Physiological Reports 7 ( 13)

6
2019
TRPM7‐mediated spontaneous Ca2+ entry regulates the proliferation and differentiation of human leukemia cell line K562

Kiriko Takahashi , Chisato Umebayashi , Tomohiro Numata , Akira Honda
Physiological Reports 6 ( 14)

7
2018
Pathophysiology and puzzles of the volume‐sensitive outwardly rectifying anion channel

Yasunobu Okada , Kaori Sato , Tomohiro Numata
The Journal of Physiology 587 ( 10) 2141 -2149

167
2009