Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases.

Kelly M Zatopek , Ece Alpaslan , Thomas C Evans , Ludovic Sauguet
Nucleic Acids Research 48 ( 21) 12204 -12218

2
2020
14
2018
Detection and Quantitation of DNA Damage on a Genome-wide Scale Using RADAR-seq

Kelly M Zatopek , Vladimir Potapov , Jennifer L Ong , Andrew F Gardner
Current Protocols 2 ( 11) e595

2022
Streamlined DNA template preparation and co-transcriptional 5′ capped RNA synthesis enabled by solid-phase catalysis

Guillermo García Marquina , Aihau Zhang , Michael Sproviero , Yi Fang
bioRxiv 2023.10. 28.564520 -2023.10. 28.564520

2023
Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases

Leonardo Betancurt-Anzola , Markel Martínez-Carranza , Marc Delarue , Kelly M Zatopek
Nature Communications 14 ( 1) 8306 -8306

1
2023
An archaeal Cas3 protein facilitates rapid recovery from DNA damage

Guy Miezner , Israela Turgeman-Grott , Kelly M Zatopek , Andrew F Gardner
microLife 4 uqad007 -uqad007

1
2023
Mapping the location, type and strand of damaged and/or mismatched nucleotides in double-stranded DNA

Kelly M Zatopek , Vladimir Potapov , Jennifer Ong , Laurence Ettwiller

2023
Enhancing Multistep DNA Processing by Solid-Phase Enzyme Catalysis on Polyethylene Glycol Coated Beads.

Shaohua Li , Aihua Zhang , Kelly Zatopek , Saba Parvez
Bioconjugate Chemistry 29 ( 7) 2316 -2324

2
2018
Extended Archaeal Histone-Based Chromatin Structure Regulates Global Gene Expression in Thermococcus kodakarensis.

Travis J Sanders , Fahad Ullah , Alexandra M Gehring , Brett W Burkhart
Frontiers in Microbiology 12 681150

2021
the DNA replication machinery as therapeutic targets

Andrew F Gardner , Zvi Kelman
Frontiers in Molecular Biosciences 6 35 -35

4
2019
Thermococcus kodakarensis TK0353 is a novel AP lyase with a new fold

Paul J Caffrey , Brian E Eckenroth , Brett W Burkhart , Kelly M Zatopek
Journal of Biological Chemistry 300 ( 1)

2024
Determinants of nucleotide sugar recognition in an archaeon DNA polymerase

Andrew F Gardner , William E Jack
Nucleic Acids Research 27 ( 12) 2545 -2553

165
1999
140
2002
Capillary electrophoresis-based functional genomics screening to discover novel archaeal DNA modifying enzymes

Kelly M Zatopek , Samantha L Fossa , Katharina Bilotti , Paul J Caffrey
Applied and Environmental Microbiology 88 ( 2) e02137 -21

4
2022
Intein splicing efficiency and RadA levels can control the mode of archaeal DNA replication

Geraldy LS Liman , Christopher W Lennon , Jaylin L Mandley , Alina M Galyon
Science Advances 10 ( 38) eadp4995 -eadp4995

2024
TelA variants, compositions, and methods

Shuang-yong Xu , Andrew F Gardner , Daniel Heiter , Pei-Chung Hsieh

2024
Platform for measuring polymerase nucleotide misincorporation kinetics reveals mechanistic differences between wild-type and engineered RNAPs

Zachariah I Carter , William B O'Brien , Andrew F Gardner
Biophysical Journal 123 ( 3) 222a -222a

2024
High-throughput Kinetics using Capillary Electrophoresis and Robotics (HiKER) platform used to Study T7, T3, and Sp6 RNA Polymerase Misincorporation

Andrew F Gardner , Zachariah Ingram Carter , Sean Robert Lund , William O'Brien
bioRxiv 2024.03. 20.585964 -2024.03. 20.585964

2024
Fusion polymerase and method for using the same

Pei-Chung Hsieh , Luo Sun , Thomas C Evans Jr , Theodore B Davis

2023