Metabolism and Function of Sphingolipids in Saccharomyces Cerevisiae: Relevance to Cancer Research

L. Ashely Cowart , Yusuf A. Hannun , Lina M. Obeid
Springer, Dordrecht 191 -210

1
2007
Roles of sphingolipid metabolism in non-alcoholic fatty liver disease (96.1)

Alton Sutter , L Cowart , Tuoyu Geng , Kenneth Chavin
The FASEB Journal 28

2014
124 Lipidomic analysis of congenital ichthyotic skin suggests disruption in ceramide catabolism

S. Rangel , E. Guttman-Yassky , A. Paller , R.L. Lefferdink
Journal of Investigative Dermatology 141 ( 5)

2021
Sphingolipids mediate formation of mRNA processing bodies during the heat-stress response of Saccharomyces cerevisiae.

L. Ashley Cowart , Jason L. Gandy , Baby Tholanikunnel , Yusuf A. Hannun
Biochemical Journal 431 ( 1) 31 -38

30
2010
Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae.

L. Ashley Cowart , Yasuo Okamoto , Xinghua Lu , Yusuf A. Hannun
Biochemical Journal 393 ( 3) 733 -740

40
2006
Structural Determinants of Active Site Binding Affinity and Metabolism by Cytochrome P450 BM-3

L.Ashley Cowart , John R. Falck , Jorge H. Capdevila
Archives of Biochemistry and Biophysics 387 ( 1) 117 -124

42
2001
THE rs72613567: TA SPLICE VARIANT OF HUMAN HSD17B13 REDUCES HEPATIC INFLAMMAGING TO AMELIORATE NONALCOHOLIC STEATOHEPATITIS AND FIBROSIS

Arun Sanyal , Mulugeta Seneshaw , Hae-Ki Min , Faridoddin Mirshahi
HEPATOLOGY 78 S1142 -S1143

2023
SPTLC3 Regulates Plasma Membrane Sphingolipid Composition to Facilitate Hepatic Gluconeogenesis

David Montefusco , Maryam Jamil , Daniel Canals , Yang Yue
Available at SSRN 4714926

Sphingolipid Involvement in Insulin Sensitivity in C2C12 Myotubes

L. Ashley Cowart , Wei Hu
The FASEB Journal 20 ( 5)

2006
Yeast sphingolipids: Recent developments in understanding biosynthesis, regulation, and function

L. Ashley Cowart , Lina M. Obeid
Biochimica et Biophysica Acta 1771 ( 3) 421 -431

105
2007
Sphingolipids in adipose tissue: What's tipping the scale?

Johana M. Lambert , Andrea K. Anderson , L. Ashley Cowart
Advances in biological regulation 70 19 -30

3
2018
Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes

Sarah Brice Russo , Catalin F. Baicu , An Van Laer , Tuoyu Geng
Journal of Clinical Investigation 122 ( 11) 3919 -3930

131
2012
Selective Substrate Supply in the Regulation of Yeastde NovoSphingolipid Synthesis

L. Ashley Cowart , Yusuf A. Hannun
Journal of Biological Chemistry 282 ( 16) 12330 -12340

63
2007
Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae

Fernando Alvarez-Vasquez , Kellie J. Sims , L. Ashley Cowart , Yasuo Okamoto
Nature 433 ( 7024) 425 -430

152
2005
The CYP4A Isoforms Hydroxylate Epoxyeicosatrienoic Acids to Form High Affinity Peroxisome Proliferator-activated Receptor Ligands

L. Ashley Cowart , Shouzuo Wei , Mei-Hui Hsu , Eric F. Johnson
Journal of Biological Chemistry 277 ( 38) 35105 -35112

179
2002
Inositol depletion induced by acute treatment of the bipolar disorder drug valproate increases levels of phytosphingosine

Shyamalagauri Jadhav , Sarah Russo , L. Ashley Cowart , Miriam L. Greenberg
Journal of Biological Chemistry 292 ( 12) 4953 -4959

4
2017
SphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes.

Tuoyu Geng , Alton Sutter , Michael D. Harland , Brittany A. Law
Journal of Lipid Research 56 ( 12) 2359 -2371

77
2015