Increased length-dependent activation of human engineered heart tissue after chronic treatment with alpha-1A-adrenergic agonist

Cassady Rupert , Elizabeth Cortez-Toledo , Javier E Lopez , Naomi C Chesler
Biophysical Journal 121 ( 3) 397a -398a

2022
Stretch Reduces Interfilament Spacing And Triggers Alterations In Thick-filament Structure In Healthy Left-atrial Fibers

Weikang Ma , Maria Papadaki , Jonathan A Kirk , Cassady Rupert
CIRCULATION RESEARCH 131

2022
Abstract P1056: Stretch Reduces Inter-filament Spacing And Triggers Alterations In Thick-filament Structure In Healthy Left-atrial Fibers

Weikang Ma , Maria Papadaki , Jonathan A Kirk , Cassady Rupert
Circulation Research 131 ( Suppl_1) AP1056 -AP1056

2022
Acute Treatment With Aficamten Rescues Contractile Function in a MyoPod Engineered Heart Tissue Model of Hypertrophic Cardiomyopathy

Cassady Rupert , Manmeet Raval , Jim J Hartman , Anne N Murphy
CIRCULATION RESEARCH 133 ( 12) E68 -E68

2023
Auxotonic MyoPod® Engineered Heart Tissues Enable Longitudinal Tracking of in vitro Development of Hypertrophic Cardiomyopathy

Cassady Rupert , Benjamin Archer , Viet Dau , Shannon Cirilli
Circulation 148 ( Suppl_1) A17931 -A17931

2023
Altered Contractile Phenotype and Sensitivity to Mavacamten in Engineered Heart Tissues With a Hypertrophic Cardiomyopathy Mutation

Cassady Rupert , Benjamin Archer , Viet Dau , Shannon Cirilli
CIRCULATION RESEARCH 131 ( 12) E175 -E175

2022
Acute Pacing Regimen Strengthens Engineered Human Cardiac Tissue

Cassady Rupert , Kelly Li , Shannon Cirilli , Xia Li
Circulation 144 ( Suppl_1) A14185 -A14185

2021
Hypertrophy Changes 3D Shape of hiPSC-Cardiomyocytes: Implications for Cellular Maturation in Regenerative Medicine

Cassady E. Rupert , Heidi H. Chang , Kareen L. K. Coulombe
Cellular and Molecular Bioengineering 10 ( 1) 54 -62

10
2017
Engineered human myocardium with local release of angiogenic proteins improves vascularization and cardiac function in injured rat hearts

Fabiola Munarin , Rajeev J. Kant , Cassady E. Rupert , Amelia Khoo
Biomaterials 251 120033

24
2020
Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques.

Cassady E. Rupert , Chinedu Irofuala , Kareen L. K. Coulombe
PLOS ONE 15 ( 3)

3
2020
29
2017
Activation of the unfolded protein response downregulates cardiac ion channels in human induced pluripotent stem cell-derived cardiomyocytes.

Man Liu , Guangbin Shi , Anyu Zhou , Cassady E. Rupert
Journal of Molecular and Cellular Cardiology 117 62 -71

19
2018
Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium.

Cassady E. Rupert , Tae Yun Kim , Bum-Rak Choi , Kareen L. K. Coulombe
Stem Cells International 2020 9363809

4
2020
Decellularized Lung Tissue Proteomics Showed Decreased Surfactant and Increased Inflammatory Proteins in the Aged Lung

JE Mcdonough , C Cosme Jr , C Rupert , JC Schupp
American Thoracic Society A3903 -A3903

2022
Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy

C Rupert , JE Lopez , E Cortez-Toledo , O De la Cruz Cabrera
American Journal of Physiology-Heart and Circulatory Physiology 324 ( 3) H293 -H304

2023
Three-Dimensional Morphological Assessment of Hypertrophy in hiPSC-derived Cardiomyocytes

C Rupert , H Chang , K Coulombe
TISSUE ENGINEERING PART A 21 S225 -S225

2015
A human in vitro cardiotoxicity model

Kareen LK Coulombe , Cassady E Rupert , Celinda M Kofron , CHOI Bum-Rak

1
2022
The roles of neuregulin-1 in cardiac development, homeostasis, and disease: supplementary issue: stem cell biology

Cassady E Rupert , Kareen LK Coulombe
Biomarker insights 10 BMI. S20061 -BMI. S20061

104
2015