David Hughes
机构: Sheffield Teaching Hospitals
每年引用次数
引用次数
引用: 10,535
H-指数: 32
I10-指数 : 52
出版物: 100
Recent advances in bone biology provide insight into the pathogenesis of bone diseases.
B F Boyce , D E Hughes , K R Wright , L Xing
Laboratory Investigation 79 ( 2) 83 -94
130
1999
Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow.
D E Hughes , B R MacDonald , R G Russell , M Gowen
Journal of Clinical Investigation 83 ( 6) 1930 -1935
329
1989
Constitutive and inducible expression of HLA class II determinants by human osteoblast-like cells in vitro.
H Skjødt , D E Hughes , P R Dobson , R G Russell
Journal of Clinical Investigation 85 ( 5) 1421 -1426
46
1990
Histological features of CIN3 and their value in predicting invasive microinvasive squamous carcinoma.
A I al-Nafussi , D E Hughes
Journal of Clinical Pathology 47 ( 9) 799 -804
35
1994
Apoptosis in bone physiology and disease.
D E Hughes , B F Boyce
Molecular pathology : MP 50 ( 3) 132 -137
103
1997
Estrogen promotes apoptosis of murine osteoclasts mediated by TGF–β
Davis E. Hughes , Aihua Dai , John C. Tiffee , He Hiu Li
Nature Medicine 2 ( 10) 1132 -1136
1,098
1996
The cellular mechanism of action of bisphosphonates.
M. Mian , D. E. Hughes , D. F. Guilland-Cumming , R. G. G. Russell
Drugs Under Experimental and Clinical Research 17 ( 2) 109 -114
37
1991
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
J. E. Fisher , M. J. Rogers , J. M. Halasy , S. P. Luckman
Proceedings of the National Academy of Sciences of the United States of America 96 ( 1) 133 -138
624
1999
Integrin expression in squamous neoplasia of the cervix
D. E. Hughes , G. Rebello , A. Al-Nafussi
The Journal of Pathology 173 ( 2) 97 -104
21
1994
Intramedullary and extramedullary fat globules on magnetic resonance imaging as a diagnostic sign for osteomyelitis
A. M. Davies , D. E. Hughes , R. J. Grimer
European Radiology 15 ( 10) 2194 -2199
30
2005
Effect of denosumab on osteolytic lesion activity after total hip arthroplasty: a single-centre, randomised, double-blind, placebo-controlled, proof of concept trial
Richard Eastell , Nigel Hoggard , Robert M Kerry , Raveen L Jayasuriya
The Lancet Rheumatology 3 ( 3)
1
2021
Trabecular bone structure in advanced chronic kidney disease: Comparison of bone biopsy assessment using microCT and histomorphometry
Richard Eastell , Syazrah Salam , David Hughes , Orla Gallagher
Bone reports 14 100827
2021
The role of static bone histomorphometry in diagnosing renal osteodystrophy
Syazrah Salam , Orla Gallagher , David Hughes , Arif Khwaja
Bone 142 115689 -115689
2021
Maternal vitamin D depletion disrupts neonatal skeletal development in mice
Harriet Buckley , Stephanie Borg , Kirsty Nicholson , Mark Kinch
Bone Abstracts 4
2015
NBAS variants causing a novel form of inherited bone fragility
Meena Balasubramanian , Jane Hurst , Catherine DeVile , Nick Bishop
Bone Abstracts 6
2017
Low-dose methotrexate in myeloproliferative neoplasm models.
Kavitha Chinnaiya , Michelle A. Lawson , Sally Thomas , Marie-Therese Haider
Haematologica 102 ( 9)
8
2017
Common genetic changes in leiomyosarcoma and gastrointestinal stromal tumour: implication for ataxia telangiectasia mutated involvement.
Aliya Ul-Hassan , Karen Sisley , David Hughes , David W. Hammond
International Journal of Experimental Pathology 90 ( 5) 549 -557
10
2009
Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis
Sindhu T Mohanty , Lucksy Kottam , Alessandra Gambardella , Martin J Nicklin
Arthritis Research & Therapy 12 ( 4) 1 -12
44
2010
The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma
Laura Forker , Piers Gaunt , Stefano Sioletic , Patrick Shenjere
British Journal of Cancer 118 ( 5) 698 -704
8
2018
Genome-Wide Analysis of Circulating Cell-Free DNA Copy Number Detects Active Melanoma and Predicts Survival.
Shobha Silva , Sarah Danson , Dawn Teare , Fiona Taylor
Clinical Chemistry 64 ( 9) 1338 -1346
5
2018