Hongbing Wang
机构: Professor of pharmaceutical sciences, University of Maryland School of Pharmacy
每年引用次数
引用次数
引用: 6,654
H-指数: 45
I10-指数 : 77
出版物: 130
Friend or Foe: Xenobiotic Activation of Nrf2 in Disease Control and Cardioprotection
William D. Hedrich , Hongbing Wang
Pharmaceutical Research 38 ( 2) 213 -241
2021
55484 Dual activation of CAR and Nrf2 improves the efficacy: toxicity ratio of cyclophosphamide and doxorubicin-based treatment of TNBC
Fengtian Xue , Linhao Li , Young Chun , Charles Hong
Journal of Clinical and Translational Science 5 98 -98
2021
3D Cell Culture Models: Drug Pharmacokinetics, Safety Assessment, and Regulatory Consideration.
Suzanne Fitzpatrick , James Hickman , Paul C Brown , Benjamin S Freedman
Clinical and Translational Science
35
2021
Activation of the Constitutive Androstane Receptor Increases the Therapeutic Index of CHOP in Lymphoma Treatment
William D. Hedrich , Jingwei Xiao , Scott Heyward , Yao Zhang
Molecular Cancer Therapeutics 15 ( 3) 392 -401
12
2016
Nuclear Receptor-Mediated Gene Regulation in Drug Metabolism
Hongbing Wang , wen xie
Pharmaceutical Sciences Encyclopedia 449 -478
2010
Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR
Antonia H. Tolson , Hongbing Wang
Advanced Drug Delivery Reviews 62 ( 13) 1238 -1249
405
2010
A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells
Leslie M. Tompkins , Haishan Li , Linhao Li , Caitlin Lynch
Biochemical Pharmacology 80 ( 11) 1754 -1761
85
2010
Comparative pharmacoproteomics of phenobarbital and citco in human primary hepatocytes
Bryan Mackowiak , Weiliang Huang , Zhihui Li , Maureen A. Kane
Drug Metabolism and Pharmacokinetics 33 ( 1) S58 -S59
2018
Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers.
Cornelia M. Smith , Stephanie R. Faucette , Hongbing Wang , Edward L. LeCluyse
Journal of Biochemical and Molecular Toxicology 19 ( 2) 96 -108
32
2005
The constitutive androstane receptor is a novel therapeutic target facilitating cyclophosphamide-based treatment of hematopoietic malignancies
Duan Wang , Linhao Li , Hui Yang , Stephen S. Ferguson
Blood 121 ( 2) 329 -338
33
2013
High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis.
Bryan Mackowiak , Linhao Li , Caitlin Lynch , Andrew Ziman
Biochemical Pharmacology 168 224 -236
7
2019
Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells
Daochuan Li , Bryan Mackowiak , Timothy G. Brayman , Michael Mitchell
Biochemical Pharmacology 98 ( 1) 190 -202
53
2015
Quantitative High-Throughput Identification of Drugs as Modulators of Human Constitutive Androstane Receptor
Caitlin Lynch , Jinghua Zhao , Ruili Huang , Jingwei Xiao
Scientific Reports 5 ( 1) 10405 -10405
28
2015
Induction of Xenobiotic Receptors, Transporters, and Drug Metabolizing Enzymes by Oxycodone
Hazem E. Hassan , Alan L. Myers , Insong J. Lee , Clifford W. Mason
Drug Metabolism and Disposition 41 ( 5) 1060 -1069
4
2013
Nuclear Translocation of Adenoviral-Enhanced Yellow Fluorescent Protein-Tagged-Human Constitutive Androstane Receptor (hCAR): A Novel Tool for Screening hCAR Activators in Human Primary Hepatocytes
Haishan Li , Tao Chen , John Cottrell , Hongbing Wang
Drug Metabolism and Disposition 37 ( 5) 1098 -1106
80
2009
Methadone induces the expression of hepatic drug-metabolizing enzymes through the activation of pregnane X receptor and constitutive androstane receptor.
Antonia H. Tolson , Haishan Li , Natalie D. Eddington , Hongbing Wang
Drug Metabolism and Disposition 37 ( 9) 1887 -1894
24
2009
Identification and Validation of Novel Human Pregnane X Receptor Activators among Prescribed Drugs via Ligand-Based Virtual Screening
Yongmei Pan , Linhao Li , Gregory Kim , Sean Ekins
Drug Metabolism and Disposition 39 ( 2) 337 -344
37
2011
DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor.
Dongdong Liang , Linhao Li , Caitlin Lynch , Benjamin Diethelm-Varela
ACS Medicinal Chemistry Letters 10 ( 7) 1039 -1044
6
2019
Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes
Caitlin Lynch , Yongmei Pan , Linhao Li , Scott Heyward
Toxicology and Applied Pharmacology 279 ( 1) 33 -42
18
2014
A Single Amino Acid Controls the Functional Switch of Human Constitutive Androstane Receptor (CAR) 1 to the Xenobiotic-Sensitive Splicing Variant CAR3
Tao Chen , Leslie M. Tompkins , Linhao Li , Haishan Li
Journal of Pharmacology and Experimental Therapeutics 332 ( 1) 106 -115
65
2010