25-OR: Investigating a Candidate Causal Allele in Type 2 Diabetes Susceptibility Gene PAM as a Cause of Neonatal Diabetes Mellitus
SHAHANA SENGUPTA , LORI L. BONNYCASTLE , BENOIT HASTOY , ANTJE GROTZ
Diabetes 68
2019
DOCTORAT DE L’UNIVERSITÉ BORDEAUX
Benoît HASTOY
Université de Bordeaux
2011
The Calcium-Sensing Receptor, a Class C GPCR, Spatially-Directs G-protein Selectivity via Endosomal Signaling.
Aylin Hanyaloglu , Patrik Rorsman , Rajesh Thakker , Benoit Hastoy
Journal of Bone and Mineral Research 32
2017
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion.
Philippe Froguel , Mickaël Canouil , Fabian L. Cardenas-Diaz , Fabian L. Cardenas-Diaz
Cell Reports 34 ( 5) 108703 -108703
9
2021
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion
Elisa Vergari , Jakob G. Knudsen , Reshma Ramracheya , Albert Salehi
Nature Communications 10 ( 1) 139
54
2019
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation
Natasha HJ Ng , Sara M Willems , Juan Fernandez , Rebecca S Fine
bioRxiv 790618
5
2019
MicroRNA-7a regulates pancreatic β cell function
Benoit Hastoy , Sofia Gargani , Julie Kerr-Conte , Francois Pattou
Journal of Clinical Investigation 124 ( 6) 2722 -2735
181
2014
Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion
Stephan C. Collins , Hyun Woong Do , Benoit Hastoy , Alison Hugill
Diabetes 65 ( 7) 1952 -1961
36
2016
GLP-1 stimulates insulin secretion by PKC-dependent Trpm4 and Trpm5 activation
Makoto Shigeto , Reshma Ramracheya , Andrei I. Tarasov , Chae Young Cha
Journal of Clinical Investigation 125 ( 12) 4714 -4728
94
2015
Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.
Soren K. Thomsen , Anne Raimondo , Benoit Hastoy , Shahana Sengupta
Nature Genetics 50 ( 8) 1122 -1131
22
2018
Loss of ZnT8 function protects against diabetes by enhanced insulin secretion
Om Prakash Dwivedi , Mikko Lehtovirta , Benoit Hastoy , Vikash Chandra
Nature Genetics 51 ( 11) 1596 -1606
34
2019
Type 2 Diabetes Risk Alleles Reveal a Role for Peptidylglycine Alpha-amidating Monooxygenase in Beta Cell Function
Anne Raimondo , Soren K. Thomsen , Benoit Hastoy , Mahesh M. Umapathysivam
bioRxiv 158642
1
2017
AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity
Caroline M. Gorvin , Angela Rogers , Benoit Hastoy , Andrei I. Tarasov
Cell Reports 22 ( 4) 1054 -1066
54
2018
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.
Ghupurjan Gheni , Masahito Ogura , Masahiro Iwasaki , Norihide Yokoi
Cell Reports 9 ( 2) 661 -673
148
2014
RFX6 regulates insulin secretion by modulating Ca2+ homeostasis in human β cells.
Vikash Chandra , Olivier Albagli-Curiel , Benoit Hastoy , Julie Piccand
Cell Reports 9 ( 6) 2206 -2218
50
2014
A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function.
Antje K. Grotz , Fernando Abaitua , Elena Navarro-Guerrero , Benoit Hastoy
Wellcome Open Research 4 150 -150
9
2019
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.
Julia Ast , Anastasia Arvaniti , Nicholas H. F. Fine , Daniela Nasteska
Nature Communications 11 ( 1) 467 -467
69
2020
NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations.
Shailesh Kumar Gupta , Agata Wesolowska-Andersen , Anna K. Ringgaard , Himjyot Jaiswal
Stem Cell Research 29 220 -231
25
2018
Fusion pore in exocytosis: More than an exit gate? A β-cell perspective
Benoit Hastoy , Anne Clark , Patrik Rorsman , Jochen Lang
Cell Calcium 68 45 -61
7
2017
Type-2 Diabetes - A Fusion Pore Disease?
Patrik Rorsman , Stephan C. Collins , Benoit Hastoy
Biophysical Journal 114 ( 3)
2018