引用次数
引用: 248
H-指数: 8
I10-指数 : 8
出版物: 13
Structural determinants of ligand binding to ATP dependent enzymes: Studies of Protein Kinase and Heat Shock Protein 70.
Dilip Narayanan
UiT Norges arktiske universitet
2017
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
Michael Gajhede , Sara M Ø Solbak , Michael Sattler , Dilip Narayanan
Journal of Medicinal Chemistry 64 ( 8) 4623 -4661
2021
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.
Kim T. Tran , Jakob S. Pallesen , Sara M. Ø. Solbak , Dilip Narayanan
Journal of Medicinal Chemistry 62 ( 17) 8028 -8052
24
2019
Data driven polypharmacological drug design for lung cancer: analyses for targeting ALK, MET, and EGFR
Dilip Narayanan , Osman A. B. S. M. Gani , Franz X. E. Gruber , Richard A. Engh
Journal of Cheminformatics 9 ( 1) 43 -43
4
2017
Targeting the Redox Landscape in Cancer Therapy.
Dilip Narayanan , Sana Ma , Dennis Özcelik
Cancers 12 ( 7) 1706
7
2020
Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches.
Osman A. Gani , Balmukund Thakkar , Dilip Narayanan , Kazi A. Alam
Biochimica et Biophysica Acta 1854 ( 10) 1605 -1616
9
2015
Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery.
Sara Marie Øie Solbak , Jie Zang , Dilip Narayanan , Lars Jakobsen Høj
Journal of Medicinal Chemistry 63 ( 3) 1156 -1177
5
2020
Evaluating the Predictivity of Virtual Screening for Abl Kinase Inhibitors to Hinder Drug Resistance
Osman A. B. S. M. Gani , Dilip Narayanan , Richard A. Engh
Chemical Biology & Drug Design 82 ( 5) 506 -519
6
2013
Targeting NOX2 with Bivalent Small-Molecule p47phox–p22phox Inhibitors
Jie Zang , Felix Peters , Yves Cambet , Eugenia Cifuentes-Pagano
Journal of Medicinal Chemistry 66 ( 21) 14963 -15005
1
2023
Development of noncovalent small-molecule Keap1-Nrf2 inhibitors by fragment-based drug discovery
Dilip Narayanan , Kim T Tran , Jakob S Pallesen , Sara MØ Solbak
Journal of medicinal chemistry 65 ( 21) 14481 -14526
16
2022
Small-molecule modulators of tumor necrosis factor signaling
Henri Chédotal , Dilip Narayanan , Katrine Povlsen , Charlotte H Gotfredsen
Drug discovery today 103575 -103575
9
2023
Structure-Guided Conformational Restriction Leading to High-Affinity, Selective, and Cell-Active Tetrahydroisoquinoline-Based Noncovalent Keap1-Nrf2 Inhibitors
Yuting Qin , Cecilie Poulsen , Dilip Narayanan , Camilla B Chan
Journal of Medicinal Chemistry
2024
Ligand‐induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity
Dilip Narayanan , Anne Sofie G Larsen , Stine Juul Gauger , Ruth Adafia
Protein Science 33 ( 10) e5152 -e5152
2024