Andrew M Kidger
机构: Postdoctoral Research Scientist, Babraham Institute
每年引用次数
引用次数
引用: 898
H-指数: 10
I10-指数 : 11
出版物: 19
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
Bradley S Ferguson , Sara A Wennersten , Kimberly M Demos-Davies , Marcello Rubino
American Journal of Physiology-Heart and Circulatory Physiology 321 ( 2) H382 -H389
3
2021
Signaling and Stress Response: DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
Bradley S Ferguson , Sara A Wennersten , Kimberly M Demos-Davies , Marcello Rubino
American Journal of Physiology-Heart and Circulatory Physiology 321 ( 2) H382
2021
Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6
Andrew M Kidger , Mark K Saville , Linda K Rushworth , Jane Davidson
Oncogene 41 ( 20) 2811 -2823
10
2022
Visualizing and quantitating the spatiotemporal regulation of Ras/ERK signaling by dual-specificity mitogen-activated protein phosphatases (MKPs)
Christopher J Caunt , Andrew M Kidger , Stephen M Keyse
Protein Tyrosine Phosphatases: Methods and Protocols 197 -215
6
2016
RAF inhibitors activate the integrated stress response by direct activation of GCN2
Rebecca Gilley , Andrew M Kidger , Graham Neill , Paul Severson
bioRxiv 2024.08. 15.607884 -2024.08. 15.607884
2024
The Regulation of Oncogenic MAP Kinase Signalling by Dual-Specificity MAP Kinase Phosphatases
Andrew M Kidger
University of Dundee
2016
Submission PDF
Andrew Kidgera , Linda Rushwortha , Julia Stellziga , Jane Davidsona
PNAS 67 68 -68
Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2.
Andrew M. Kidger , Joanne M. Munck , Harpreet K. Saini , Kathryn Balmanno
Molecular Cancer Therapeutics 19 ( 2) 525 -539
3
2020
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors.
Pamela A. Lochhead , Julie A. Tucker , Natalie J. Tatum , Jinhua Wang
Nature Communications 11 ( 1) 1383
6
2020
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Andrew M. Kidger , James Sipthorp , Simon J. Cook
Pharmacology & Therapeutics 187 45 -60
64
2018
The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)
Andrew M. Kidger , Stephen M. Keyse
Seminars in Cell & Developmental Biology 50 125 -132
117
2016
De‐RSKing ERK – regulation of ERK1/2‐RSK dissociation by phosphorylation within a disordered motif
Andrew M. Kidger , Simon J. Cook
FEBS Journal 285 ( 1) 42 -45
1
2018
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis.
Richard I. Odle , Simon A. Walker , David Oxley , Andrew M. Kidger
Molecular Cell 77 ( 2)
15
2020
Dual-specificity MAP kinase phosphatases in health and disease.
Ole-Morten Seternes , Andrew M. Kidger , Stephen M. Keyse
Biochimica et Biophysica Acta 1866 ( 1) 124 -143
30
2019
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling.
Andrew M. Kidger , Linda K. Rushworth , Julia Stellzig , Jane Davidson
Proceedings of the National Academy of Sciences of the United States of America 114 ( 3) 201614684
37
2017
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression
Linda K. Rushworth , Andrew M. Kidger , Laurent Delavaine , Graeme Stewart
Proceedings of the National Academy of Sciences of the United States of America 111 ( 51) 18267 -18272
46
2014
Visualization of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe
James Sipthorp , Honorine Lebraud , Rebecca Gilley , Andrew M. Kidger
Bioconjugate Chemistry 28 ( 6) 1677 -1683
7
2017
Dual-Specificity Map Kinase (MAPK) Phosphatases (MKPs) and Their Involvement in Cancer
Andrew M. Kidger , Stephen M. Keyse
Protein Tyrosine Phosphatases in Cancer 201 -231
2
2016
ERK1/2 inhibitors act as monovalent degraders inducing ubiquitylation and proteasome-dependent turnover of ERK2, but not ERK1
K Balmanno , AM Kidger , DP Byrne , MJ Sale
Biochemical Journal 480 ( 9) 587 -605
3
2023