引用次数
引用: 2,075
H-指数: 23
I10-指数 : 27
出版物: 79
Abstract P6-15-14: Inhibit SIAH E3 Ligase, a Downstream Signaling Module Required for the HER2/EGFR/RAS Signal Transduction, To Block Tumorigenesis and Metastasis of Highly Invasive Human Breast Cancers
AH Tang , CH Park , Y Liao , AU Ahmed
Cancer Research 70
2010
Pentobarbital-induced Changes in Drosophila Glutathione S-Transferase D21 mRNA Stability
Amy Hong Tang , Chen-Pei D. Tu
Journal of Biological Chemistry 270 ( 23) 13819 -13825
74
1995
The Drosophila glutathione S-transferasegstD genes: Expression, regulation and biochemical functions.
Amy Hong Tang
0662 -0662
4
1996
RAS pathway biomarkers for breast cancer prognosis.
Lauren L Siewertsz van Reesema , Vasilena Zheleva , Janet S Winston , Amy H Tang
Clinical laboratory international 40 18 -23
5
2016
PHYL Acts to Down-Regulate TTK88, a Transcriptional Repressor of Neuronal Cell Fates, by a SINA-Dependent Mechanism
Amy H Tang , Thomas P Neufeld , Elaine Kwan , Gerald M Rubin
Cell 90 ( 3) 459 -467
216
1997
Targeting SIAH2-dependent proteolysis downstream of the HER2/EGFR/RAS signaling pathway to inhibit tumorigenesis and metastasis of highly invasive human breast cancer
Cheol Hong Park , Yang Liao , Atique U Ahmed , Nanette R Reed
Cancer Research 71 ( 8_Supplement) 1659 -1659
2011
Targeting SIAH2 E3 ligase to inhibit HER2/EGFR/RAS activation and to block tumorigenesis and metastasis of highly invasive human breast cancer cells
Cheol Hong Park , Yang Liao , Atique U Ahmed , Nanette R Reed
Cancer Research 70 ( 8_Supplement) 4518 -4518
2010
Attacking the most downstream" gatekeeper," the SIAH-dependent proteolytic machinery, in the oncogenic ERBB/K-RAS signaling pathway to block tumorigenesis and control metastasis in human cancer
Minglei Bian , Yang Liao , Vasilena Zheleva , Zena Urban
MOLECULAR CANCER RESEARCH 12
2014
Inhibition of SIAH E3 ligase function leads to increased cell death in metastatic human cancer cells
Zena M Urban , Lauren van Reesema , Minglei Bian , Thomas C Smyrk
Cancer Research 74 ( 19_Supplement) 4442 -4442
2014
Attacking the most downstream" gatekeeper" signaling module in the oncogenic ERBB/K-RAS signaling pathway to block tumorigenesis and metastasis in human cancer
Minglei Bian , Yang Liao , Vasilena Zheleva , Xiaofei Gao
CANCER RESEARCH 73
2013
Make a difference and save lives in human metastatic cancer by attacking the Achilles heel in the oncogenic ERBB/K-RAS signaling pathway
Amy H Tang , Yang Liao , Minglei Bian , Vasliena Zheleva
CANCER RESEARCH 73
2013
Seven‐In‐Absentia (SINA) Family E3 Ligases in Development and Growth
Robert E Van Sciver , Yajun Cao , Atique U Ahmed , Amy H Tang
The FASEB Journal 32 533.52 -533.52
2018
The “gatekeeper” function of Drosophila Seven-IN-Absentia (SINA) E3 ligase and its human homologs, SIAH1 and SIAH2, is highly conserved for proper RAS signal transduction in Drosophila development
Robert E Van Sciver , Yajun Cao , Atique U Ahmed , Amy H Tang
Cancer Research 77 ( 13_Supplement) 4824 -4824
2017
Evolutionary clues to the functions of the Toll-like family as surveillance receptors
Geoffrey B Johnson , Gregory J Brunn , Amy H Tang , Jeffrey L Platt
Trends in Immunology 24 ( 1) 19 -24
88
2003
Infection‐induced proteolysis of PGRP‐LC controls the IMD activation and melanization cascades in Drosophila
Rebecca L Schmidt , Theodore R Trejo , Timothy B Plummer , Jeffrey L Platt
The FASEB Journal 22 ( 3) 918 -929
86
2008
Abstract B40: SIAH-dependent SMAD2/3/4 ubiquitination and degradation in mediating the K-RAS-TGFβ antagonism during tumorigenesis and metastasis in human pancreatic cancer cells.
Amy H Tang , Yang Liao , Maryanne Edens , Ralf Janknecht
Cancer Research 72
2012
SIAH2 E3 ligase targets LIM-domain proteins for degradation to modulate focal adhesion and cell motility
Minglei Bian , Yang Liao , Monicah Njogu , Rebecca Schmidt
Cancer Research 76 ( 14_Supplement) 5049 -5049
2016
Abstract A26: Attacking the most downstream “gatekeeper,” the SIAH-dependent proteolytic machinery, in the oncogenic ERBB/K-RAS signaling pathway to block tumorigenesis and control metastasis in human cancer
Minglei Bian , Yang Liao , Vasilena Zheleva , Zena Urban
Molecular Cancer Research 12
2014
Inhibiting SIAH2 E3 ligase function disrupts focal adhesion and cell junction, inhibits cell mobility and attachment, and blocks tumor invasion and metastasis in oncogenic K-Ras-driven tumors
Ming Bian , Yang Liao , Rebecca L Schmidt , Monicah M Njogu
Cancer Research 74 ( 19_Supplement) 1965 -1965
2014
Abstract C62: Attacking the most downstream “gatekeeper” signaling module in the oncogenic ERBB/K-RAS signaling pathway to block tumorigenesis and metastasis in human cancer
Minglei Bian , Yang Liao , Vasilena Zheleva , Xiaofei Gao
Cancer Research 73
2013