Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis

Michal Hlavac , Annika Dwucet , Richard Eric Kast , Jens Engelke
Cellular Oncology 42 ( 3) 287 -301

3
2019
Conditioning response to granulocyte colony‐stimulating factor via the dipeptidyl peptidase IV‐adenosine deaminase complex

Daniele Focosi , Richard Eric Kast , Sara Galimberti , Mario Petrini
Journal of Leukocyte Biology 84 ( 2) 331 -337

7
2008
JC virus DNA in healthy brain tissue: a challenge for progressive multifocal leukoencephalopathy diagnosis.

Daniele Focosi , Richard Eric Kast , Fabrizio Maggi , Luca Ceccherini-Nelli
Annals of Neurology 65 ( 2) 230 -230

3
2009
Risperidone-induced reduction in JC viruria as a surrogate marker for efficacy against progressive multifocal leukoencephalopathy and hemorrhagic cystitis.

Daniele Focosi , Richard Eric Kast , Fabrizio Maggi , Luca Ceccherini-Nelli
Journal of Clinical Virology 39 ( 1) 63 -64

17
2007
Hypothesis: central nervous system delivery of cyclosporine A for therapy of progressive multifocal leukoencephalopathy.

Daniele Focosi , Richard Eric Kast , Fabrizio Maggi , Linda Vatteroni
Journal of Clinical Virology 39 ( 2) 156 -158

3
2007
Sialic acid moieties and 5-HT2a: two faces of the same receptor for JC virus?

Daniele Focosi , Richard Eric Kast , Fabrizio Maggi , Luca Ceccherini-Nelli
Journal of Clinical Virology 43 ( 1) 132 -133

5
2008
EXTH-45. THE REPURPOSED CUSP9 REGIMEN EXERTS POTENT ANTI-NEOPLASTIC ACTIVITY AGAINST GLIOBLASTOMA CELLS IN VITRO

Marc-Eric Halatsch , Richard Eric Kast , Annika Dwucet , Markus Siegelin
Neuro-oncology 20

2018
EXTH-54. Bcl-2/Bcl-xL INHIBITION SYNERGISTICALLY ENHANCES THE ANTI-NEOPLASTIC ACTIVITY OF CUSP9 AGAINST GLIOBLASTOMA CELLS IN VITRO

Marc-Eric Halatsch , Richard Eric Kast , Annika Dwucet , Christian Rainer Wirtz
Neuro-oncology 20

2018
EXTH-55. CONCOMITANT INHIBITION OF RAC1 AND Bcl-2/Bcl-xL INTERFERES WITH THE Mcl-1/Usp9X AXIS AND YIELDS SYNERGISTIC ANTI-GLIOMA ACTIVITY

Michal Hlavac , Annika Dwucet , Mike-Andrew Westhoff , Richard Eric Kast
Neuro-oncology 20

2018
Olanzapine inhibits proliferation, migration and anchorage- independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect

Georg Karpel-Massler , Richard Eric Kast , Mike-Andrew Westhoff , Annika Dwucet
Journal of Neuro-oncology 122 ( 1) 21 -33

29
2015
Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma.

Andrej Pala , Georg Karpel-Massler , Richard Eric Kast , Christian Rainer Wirtz
Cancers 4 ( 2) 523 -530

19
2012
Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose induces energy depletion and synergistic anti-cancer activity in glioblastoma.

Maximilian Pruss , Annika Dwucet , Mine Tanriover , Michal Hlavac
British Journal of Cancer 122 ( 8) 1146 -1157

9
2020
The strange connection between epidermal growth factor receptor tyrosine kinase inhibitors and dapsone: from rash mitigation to the increase in anti-tumor activity.

Mariarosaria Boccellino , Lucio Quagliuolo , Concetta Alaia , Anna Grimaldi
Current Medical Research and Opinion 32 ( 11) 1839 -1848

11
2016
Phenobarbital-associated bone marrow aplasia: a case report and review of the literature.

Daniele Focosi , Richard Eric Kast , Edoardo Benedetti , Federico Papineschi
Acta Haematologica 119 ( 1) 18 -21

8
2008
Progressive Multifocal Leukoencephalopathy: What’s New?

Daniele Focosi , Tuccori Marco , Richard Eric Kast , Fabrizio Maggi
The Neuroscientist 16 ( 3) 308 -323

23
2010
JC viremia and multiple sclerosis.

Daniele Focosi , Richard Eric Kast , Mario Petrini
Journal of NeuroVirology 14 ( 1) 85 -86

2
2008
Bcl-2/Bcl-xL inhibition predominantly synergistically enhances the anti-neoplastic activity of a low-dose CUSP9 repurposed drug regime against glioblastoma.

Marc‐Eric Halatsch , Richard Eric Kast , Annika Dwucet , Michal Hlavac
British Journal of Pharmacology 176 ( 18) 3681 -3694

12
2019
Gliptins

Daniele Focosi , Richard Eric Kast , Mario Petrini
The Lancet 369 ( 9558) 0 -270

2007