作者: Marco L. Davila
DOI:
关键词: Cell 、 Antigen 、 Immune system 、 Binding domain 、 Viral vector 、 Cell biology 、 Heparin 、 Chemistry 、 Cancer immunotherapy 、 Chimeric antigen receptor
摘要: Disclosed are compositions and methods for gene transfer in immune effector cells, e.g. to create chimeric antigen receptors (CARs). In particular, polypeptides disclosed that comprising an antigen-binding region a heparin binding domain, wherein the is capable of specifically cell located on cell, domain viral vector.