β-Ionone and its analogs as promising anticancer agents.

作者: Mahsa Ansari , Saeed Emami

DOI: 10.1016/J.EJMECH.2016.07.037

关键词: Cancer cellCancer preventionIn vivoCell growthChemistryPharmacologySignal transductionCancer researchApoptosisIn vitroIonone

摘要: β-Ionone is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables. Recent studies have demonstrated anti-proliferative, anti-metastatic apoptosis induction properties β-ionone vitro vivo. Also, the focused on investigating action different types malignant cells possible mechanisms action. Moreover, quest new synthetic β-ionone-based compounds possessing activities may enable discovery can be used combination regimes thus overcoming tumor resistance to conventional anticancer agents. These agents will also useful for targeting distinct signaling pathways, activate selectively cancer but devoid undesirable side effects. In this paper, we reviewed potentialities related prevention chemotherapy.

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