Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes
作者： Meda E. Pavkov , Peter H. Bennett , Maurice L. Sievers , Jonathan Krakoff , Desmond E. Williams
DOI: 10.1111/J.1523-1755.2005.00523.X
关键词: Renal replacement therapy 、 Gastroenterology 、 Kidney disease 、 Endocrinology 、 Type 2 diabetes 、 Creatinine 、 Renal function 、 Nephrology 、 Medicine 、 Internal medicine 、 Proteinuria 、 Diabetes mellitus
摘要: Predominant effect of kidney disease on mortality in Pima Indians with or without type 2 diabetes. Background We examined the (KD) nondiabetic and diabetic aged ≥45 years old. Methods Deaths person-years follow-up were stratified a time-dependent fashion into categories ( 1 ) no proteinuria normal serum creatinine (SCr); SCr; 3 high SCr [SCr ≥133 μmol/L (1.5 mg/dL) men, ≥124 (1.4 women] but not renal replacement therapy (RRT); 4 RRT. Results Among 1993 subjects, 55.8% had diabetes at baseline. Overall death rates increased declining function both subjects P = 0.0001) was highest those RRT Conclusion Death comparably worsening similar KD. KD associated excess from DN, CVD, infections, malignancy infections
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