Inhibition of multi-species oral biofilm by bromide doped bioactive glass

摘要: Bioactive glass is an attractive biomaterial that has shown excellent osteogenic and angiogenic effects for oral bone repairing procedures. However, anti-biofilm potential related to such not been completely validated, mainly against multi-species biofilms involved in early tissue infections. The aim of the present study was evaluate effect 58 S bioactive embedding calcium bromide compounds at different concentrations. free or containing 5, 10 wt % CaBr2 synthesized by alkali sol-gel method then characterized physco-chemical analyses scanning electron microscopy (SEM). Then, samples were tested microbiological assays using optical density, real time q-PCR, SEM. particles showed accurate chemical composition angular shape with a bimodal size distribution ranging from 0.6 110 µm. mean particle around 29 Anti-biofilm recorded 5 -doped S. mitis, V. parvula, P. gingivais, gordoni, A. viscosus, F, nucleatum, gingivais. F. gingivalis. Such species are biofilm structure infections on hard soft tissues cavity. incorporation into can be strategy enhance glasses healing infection treatment. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1994-2003, 2017.