Dynamic malaria hotspots in an open cohort in western Kenya.

作者: Alyssa Platt , Andrew A. Obala , Charlie MacIntyre , Barasa Otsyula , Wendy Prudhomme O’ Meara

DOI: 10.1038/S41598-017-13801-6

关键词: Average levelGeographyDemographyMalariaCohortRegression analysisHotspot (geology)Human migrationPopulationTransmission intensity

摘要: Malaria hotspots, defined as areas where transmission intensity exceeds the average level, become more pronounced declines. Targeting hotspots may accelerate reductions in and could be pivotal for malaria elimination. Determinants of hotspot location, particularly their movement, are poorly understood. We used spatial statistical methods to identify foci incidence self-reported a large census population 64,000 people, 8,290 compounds over 2.5-year study period. Regression models examine stability static dynamic correlates with location. Hotspot location changed short time-periods, rarely recurring same area. Hotspots identified spring versus fall season differed stability. Households located were likely following (RR = 1.77, 95% CI: 1.66–1.89), but opposite was true (RR = 0.15, 0.08–0.28). Location within related environmental household characteristics such distance roads or rivers. Human migration into correlated risk membership, direction association based on origin event.

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