Mechanistic Insights into TiO2 and ZnO Nanoparticle-Induced Metabolic Changes in Escherichia coli Under Solar Simulated Light Irradiation

作者: Kavitha Pathakoti , Manjunath Manubolu , Huey-min Hwang

DOI: 10.1007/S11270-019-4388-2

关键词: PutrescineArginineBiochemistryMetabolic pathwayGlycineOxidative stressPolyamineSerineChemistryEscherichia coli

摘要: This study investigated the metabolic response of E. coli after exposure to TiO2 and ZnO NPs under solar simulated irradiation. A total 14 altered metabolites involved in two pathways were recognized using multivariate analysis. Polyamine, putrescine was elevated ZnO-treated group, as an adaptation oxidative stress cells, whereas it significantly reduced TiO2-treated group. Glycine levels also both treatment groups, showing cellular protection cells exposure. In addition, glycine, serine, threonine metabolism arginine proline groups respectively.

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