Simian Immunodeficiency Viruses and the Origin of HIVs

摘要: Reconstruction of the phylogenetic relationships between human lentiviruses responsible for AIDS epidemic and from African nonhuman primates can help clarify origin pandemic. These studies have several scientific—and public health—implications, although detailed circumstances such zoonotic events are still not fully understood. As potential simian-to-simian, simian-tohuman, human-to-human transmission becomes better understood, emergence new and/or more virulent lentiviral strains, capable causing epidemics, needs to be considered. Multidisciplinary field remain important. It also appears clear that simian infections advance our understanding HIV’s pathogenesis, an necessary development effective vaccines therapeutics.