New concepts of vitamin D functions.

作者: HECTOR F. DeLUCA

DOI: 10.1111/J.1749-6632.1992.TB17089.X

关键词: CalcitriolHormoneParathyroid hormoneInternal medicineCalciumEndocrinologyCalcium metabolismVitaminVitamin D and neurologyCalbindinChemistry

摘要: Besides its classical actions in calcium metabolism, it is clear that the hormonal form of vitamin D has many new functions, which have only been discovered as a result following appearance receptor. Furthermore, because D-based endocrine system, use compounds treating variety diseases expanded. We now know 1.25-(OH)2D3 not stimulates intestine to absorb and phosphorus, bones mobilize kidney cause increased renal reabsorption calcium, but also directly suppresses parathyroid hormone developmental necessary for recruitment cells osteoclast formation, female reproduction, development skin, treatment certain malignant conditions.

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